Matches in SemOpenAlex for { <https://semopenalex.org/work/W1937265712> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1937265712 endingPage "111" @default.
- W1937265712 startingPage "95" @default.
- W1937265712 abstract "ABSTRACT Previous work has shown that cultured kératinocytes do not form desmosomes at low [Ca2+] (<0·l mM) but may be induced to do so by raising [Ca2+] to physiological levels (l·8–2mM). Here, fluorescent antibody staining with specific anti-desmosomal antibodies and electron microscopy have been used to determine whether Ca2+-induced desmosome formation also occurs in simple epithelial cells. Both Madin-Darby canine and bovine kidney cells (MDCK and MDBK) exhibit Ca2+-induced desmosome formation, but there are significant differences between them. MDCK cells resemble kératinocytes in showing showing rapid desmosome formation characterized by the simultaneous appearance of four desmosomal antigens at the cell periphery within 15–20 min of raising the [Ca2+]. In contrast MDBK cells take between 7 and 8 h to form desmosomes after Ca2+ switching, and this is characterized by slow appearance of two desmosomal antigens, the 175–164 (×103)Mr glycoprotein and desmoplakin, at the cell periphery. Differences in the pattern of staining for desmosomal antigens between the two cell types in low and high [Ca2+] are described and discussed in relation to desmosome formation and internalization. Triton X-100 extractability of desmosomal antigen staining is also considered. While most is non-extractable, staining for the glycoproteins known as desmocollins is completely extractable from MDCK cells in low [Ca2+], but that which reaches the cell periphery after Ca2+ switching becomes non-extractable. Although neither cell type forms desmosomes in low [Ca2+], both possess zonulae adhaerentes, suggesting a difference in Ca2+ requirement for formation of these two junctions." @default.
- W1937265712 created "2016-06-24" @default.
- W1937265712 creator A5027121029 @default.
- W1937265712 creator A5081261971 @default.
- W1937265712 date "1986-09-01" @default.
- W1937265712 modified "2023-09-26" @default.
- W1937265712 title "Calcium-induced desmosome formation in cultured kidney epithelial cells" @default.
- W1937265712 cites W1776006349 @default.
- W1937265712 cites W1964629984 @default.
- W1937265712 cites W1970824827 @default.
- W1937265712 cites W2001716659 @default.
- W1937265712 cites W2025033304 @default.
- W1937265712 cites W2028224423 @default.
- W1937265712 cites W2031221589 @default.
- W1937265712 cites W2038085058 @default.
- W1937265712 cites W2045508596 @default.
- W1937265712 cites W2047683729 @default.
- W1937265712 cites W2059524698 @default.
- W1937265712 cites W2073862596 @default.
- W1937265712 cites W2082200318 @default.
- W1937265712 cites W2090312642 @default.
- W1937265712 cites W2102451819 @default.
- W1937265712 cites W2113737248 @default.
- W1937265712 cites W2132452783 @default.
- W1937265712 cites W2148401717 @default.
- W1937265712 cites W2154636794 @default.
- W1937265712 cites W2162542477 @default.
- W1937265712 cites W2169496478 @default.
- W1937265712 cites W2205721839 @default.
- W1937265712 cites W2229071379 @default.
- W1937265712 cites W2263422143 @default.
- W1937265712 cites W2404456217 @default.
- W1937265712 cites W2408378836 @default.
- W1937265712 cites W2410458792 @default.
- W1937265712 cites W2419252647 @default.
- W1937265712 cites W89317624 @default.
- W1937265712 doi "https://doi.org/10.1242/jcs.85.1.95" @default.
- W1937265712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3793798" @default.
- W1937265712 hasPublicationYear "1986" @default.
- W1937265712 type Work @default.
- W1937265712 sameAs 1937265712 @default.
- W1937265712 citedByCount "82" @default.
- W1937265712 countsByYear W19372657122012 @default.
- W1937265712 countsByYear W19372657122013 @default.
- W1937265712 countsByYear W19372657122015 @default.
- W1937265712 countsByYear W19372657122016 @default.
- W1937265712 countsByYear W19372657122019 @default.
- W1937265712 crossrefType "journal-article" @default.
- W1937265712 hasAuthorship W1937265712A5027121029 @default.
- W1937265712 hasAuthorship W1937265712A5081261971 @default.
- W1937265712 hasConcept C147483822 @default.
- W1937265712 hasConcept C1491633281 @default.
- W1937265712 hasConcept C153911025 @default.
- W1937265712 hasConcept C203014093 @default.
- W1937265712 hasConcept C2777189754 @default.
- W1937265712 hasConcept C2778757060 @default.
- W1937265712 hasConcept C54355233 @default.
- W1937265712 hasConcept C55493867 @default.
- W1937265712 hasConcept C74864618 @default.
- W1937265712 hasConcept C81885089 @default.
- W1937265712 hasConcept C86803240 @default.
- W1937265712 hasConcept C95444343 @default.
- W1937265712 hasConceptScore W1937265712C147483822 @default.
- W1937265712 hasConceptScore W1937265712C1491633281 @default.
- W1937265712 hasConceptScore W1937265712C153911025 @default.
- W1937265712 hasConceptScore W1937265712C203014093 @default.
- W1937265712 hasConceptScore W1937265712C2777189754 @default.
- W1937265712 hasConceptScore W1937265712C2778757060 @default.
- W1937265712 hasConceptScore W1937265712C54355233 @default.
- W1937265712 hasConceptScore W1937265712C55493867 @default.
- W1937265712 hasConceptScore W1937265712C74864618 @default.
- W1937265712 hasConceptScore W1937265712C81885089 @default.
- W1937265712 hasConceptScore W1937265712C86803240 @default.
- W1937265712 hasConceptScore W1937265712C95444343 @default.
- W1937265712 hasIssue "1" @default.
- W1937265712 hasLocation W19372657121 @default.
- W1937265712 hasLocation W19372657122 @default.
- W1937265712 hasOpenAccess W1937265712 @default.
- W1937265712 hasPrimaryLocation W19372657121 @default.
- W1937265712 hasRelatedWork W2004150388 @default.
- W1937265712 hasRelatedWork W2015367164 @default.
- W1937265712 hasRelatedWork W2029869325 @default.
- W1937265712 hasRelatedWork W2090334013 @default.
- W1937265712 hasRelatedWork W2131736369 @default.
- W1937265712 hasRelatedWork W2156707156 @default.
- W1937265712 hasRelatedWork W2366119997 @default.
- W1937265712 hasRelatedWork W2975523360 @default.
- W1937265712 hasRelatedWork W3093662229 @default.
- W1937265712 hasRelatedWork W4283400512 @default.
- W1937265712 hasVolume "85" @default.
- W1937265712 isParatext "false" @default.
- W1937265712 isRetracted "false" @default.
- W1937265712 magId "1937265712" @default.
- W1937265712 workType "article" @default.