Matches in SemOpenAlex for { <https://semopenalex.org/work/W1937280716> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W1937280716 endingPage "1130" @default.
- W1937280716 startingPage "1126" @default.
- W1937280716 abstract "Abstract When purified murine plasminogen was added to cultures of mouse spleen B cells, active plasmin progressively appeared in the supernatants. This reaction, resulting from the specific cleavage of the plasminogen by lymphocyte plasminogen activator (LPA), was measured in a fibrinolysis assay using 125I-fibrinogen. T cells were totally ineffective; under certain conditions, they could even antagonize the B cell action. Of the various B populations studied, i.e., obtained from spleen, lymph nodes, or blood of various mouse strains, all expressed the same property of plasminogen activation, which concerned mainly medium-sized B cells. Since only slight activities were detected in extracellular or intracellular compartments, a membrane-associated proteolytic enzyme may be responsible for plasminogen activation. Submitted to a series of group-specific antiproteases, the lymphocyte plasminogen activator essentially behaved as a serine-protease, with sensitivity to diisopropyl fluorophosphate, phenyl methyl sulfonyl fluoride, and nitro phenyl guanidino benzoate. The fast renewal of the enzyme in the membrane was also demonstrated by different techniques, using modifiers of cell physiology, like cycloheximide and dexamethasone, or following the reexpression of the enzyme by the cell kinetically." @default.
- W1937280716 created "2016-06-24" @default.
- W1937280716 creator A5014509746 @default.
- W1937280716 creator A5055787416 @default.
- W1937280716 date "1981-03-01" @default.
- W1937280716 modified "2023-10-17" @default.
- W1937280716 title "Plasminogen activation by normal B lymphocytes, a function associated with the cell membrane." @default.
- W1937280716 doi "https://doi.org/10.4049/jimmunol.126.3.1126" @default.
- W1937280716 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6161960" @default.
- W1937280716 hasPublicationYear "1981" @default.
- W1937280716 type Work @default.
- W1937280716 sameAs 1937280716 @default.
- W1937280716 citedByCount "13" @default.
- W1937280716 crossrefType "journal-article" @default.
- W1937280716 hasAuthorship W1937280716A5014509746 @default.
- W1937280716 hasAuthorship W1937280716A5055787416 @default.
- W1937280716 hasBestOaLocation W19372807161 @default.
- W1937280716 hasConcept C134018914 @default.
- W1937280716 hasConcept C153911025 @default.
- W1937280716 hasConcept C181199279 @default.
- W1937280716 hasConcept C185592680 @default.
- W1937280716 hasConcept C2776572282 @default.
- W1937280716 hasConcept C2776714187 @default.
- W1937280716 hasConcept C2776873056 @default.
- W1937280716 hasConcept C2777807008 @default.
- W1937280716 hasConcept C2778128677 @default.
- W1937280716 hasConcept C2778775115 @default.
- W1937280716 hasConcept C2779679481 @default.
- W1937280716 hasConcept C2781071845 @default.
- W1937280716 hasConcept C28406088 @default.
- W1937280716 hasConcept C3675279 @default.
- W1937280716 hasConcept C55493867 @default.
- W1937280716 hasConcept C79879829 @default.
- W1937280716 hasConcept C86803240 @default.
- W1937280716 hasConceptScore W1937280716C134018914 @default.
- W1937280716 hasConceptScore W1937280716C153911025 @default.
- W1937280716 hasConceptScore W1937280716C181199279 @default.
- W1937280716 hasConceptScore W1937280716C185592680 @default.
- W1937280716 hasConceptScore W1937280716C2776572282 @default.
- W1937280716 hasConceptScore W1937280716C2776714187 @default.
- W1937280716 hasConceptScore W1937280716C2776873056 @default.
- W1937280716 hasConceptScore W1937280716C2777807008 @default.
- W1937280716 hasConceptScore W1937280716C2778128677 @default.
- W1937280716 hasConceptScore W1937280716C2778775115 @default.
- W1937280716 hasConceptScore W1937280716C2779679481 @default.
- W1937280716 hasConceptScore W1937280716C2781071845 @default.
- W1937280716 hasConceptScore W1937280716C28406088 @default.
- W1937280716 hasConceptScore W1937280716C3675279 @default.
- W1937280716 hasConceptScore W1937280716C55493867 @default.
- W1937280716 hasConceptScore W1937280716C79879829 @default.
- W1937280716 hasConceptScore W1937280716C86803240 @default.
- W1937280716 hasIssue "3" @default.
- W1937280716 hasLocation W19372807161 @default.
- W1937280716 hasLocation W19372807162 @default.
- W1937280716 hasOpenAccess W1937280716 @default.
- W1937280716 hasPrimaryLocation W19372807161 @default.
- W1937280716 hasRelatedWork W167177991 @default.
- W1937280716 hasRelatedWork W173227074 @default.
- W1937280716 hasRelatedWork W1839872044 @default.
- W1937280716 hasRelatedWork W1964386731 @default.
- W1937280716 hasRelatedWork W2007255678 @default.
- W1937280716 hasRelatedWork W2065926578 @default.
- W1937280716 hasRelatedWork W2087576130 @default.
- W1937280716 hasRelatedWork W2097830168 @default.
- W1937280716 hasRelatedWork W2412196522 @default.
- W1937280716 hasRelatedWork W29122585 @default.
- W1937280716 hasVolume "126" @default.
- W1937280716 isParatext "false" @default.
- W1937280716 isRetracted "false" @default.
- W1937280716 magId "1937280716" @default.
- W1937280716 workType "article" @default.