Matches in SemOpenAlex for { <https://semopenalex.org/work/W1937292223> ?p ?o ?g. }
- W1937292223 endingPage "1739" @default.
- W1937292223 startingPage "1729" @default.
- W1937292223 abstract "The treatment of acute lymphoblastic leukemia (ALL) in adults remains challenging and novel therapies are needed. The antigen, CD19, is expressed by >90% of pre-B ALLs and represents an attractive therapeutic target. The bispecific T-cell-engaging antibody, blinatumomab, targets CD19 and has demonstrated encouraging results in minimal residual disease positive and relapsed/refractory pre-B ALL. In this review, we discuss in detail the mechanism of action and key pharmacologic aspects of blinatumomab. In addition, the preclinical studies, clinical studies and toxicities are summarized." @default.
- W1937292223 created "2016-06-24" @default.
- W1937292223 creator A5026731813 @default.
- W1937292223 creator A5032863911 @default.
- W1937292223 creator A5082944296 @default.
- W1937292223 date "2015-06-01" @default.
- W1937292223 modified "2023-09-26" @default.
- W1937292223 title "Structure, development, preclinical and clinical efficacy of blinatumomab in acute lymphoblastic leukemia" @default.
- W1937292223 cites W1195517392 @default.
- W1937292223 cites W1433367056 @default.
- W1937292223 cites W1570928653 @default.
- W1937292223 cites W1572252257 @default.
- W1937292223 cites W1685744202 @default.
- W1937292223 cites W1840766718 @default.
- W1937292223 cites W1967512987 @default.
- W1937292223 cites W1972019659 @default.
- W1937292223 cites W1977380325 @default.
- W1937292223 cites W1983522573 @default.
- W1937292223 cites W1991644988 @default.
- W1937292223 cites W1996815863 @default.
- W1937292223 cites W2015956932 @default.
- W1937292223 cites W2016833582 @default.
- W1937292223 cites W2028487240 @default.
- W1937292223 cites W2031452426 @default.
- W1937292223 cites W2037557556 @default.
- W1937292223 cites W2037873230 @default.
- W1937292223 cites W2038139667 @default.
- W1937292223 cites W2038414910 @default.
- W1937292223 cites W2061585822 @default.
- W1937292223 cites W2066508515 @default.
- W1937292223 cites W2067557607 @default.
- W1937292223 cites W2076560655 @default.
- W1937292223 cites W2076787465 @default.
- W1937292223 cites W2081127271 @default.
- W1937292223 cites W2083494119 @default.
- W1937292223 cites W2091264926 @default.
- W1937292223 cites W2096649209 @default.
- W1937292223 cites W2104187048 @default.
- W1937292223 cites W2107685938 @default.
- W1937292223 cites W2107925822 @default.
- W1937292223 cites W2109909062 @default.
- W1937292223 cites W2118241155 @default.
- W1937292223 cites W2127742735 @default.
- W1937292223 cites W2130011407 @default.
- W1937292223 cites W2130338247 @default.
- W1937292223 cites W2131388477 @default.
- W1937292223 cites W2136627573 @default.
- W1937292223 cites W2160881482 @default.
- W1937292223 cites W2169961966 @default.
- W1937292223 cites W2416430600 @default.
- W1937292223 cites W2549823948 @default.
- W1937292223 cites W2979774568 @default.
- W1937292223 cites W33007984 @default.
- W1937292223 cites W4376542656 @default.
- W1937292223 cites W996750591 @default.
- W1937292223 doi "https://doi.org/10.2217/fon.15.84" @default.
- W1937292223 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26075441" @default.
- W1937292223 hasPublicationYear "2015" @default.
- W1937292223 type Work @default.
- W1937292223 sameAs 1937292223 @default.
- W1937292223 citedByCount "10" @default.
- W1937292223 countsByYear W19372922232015 @default.
- W1937292223 countsByYear W19372922232016 @default.
- W1937292223 countsByYear W19372922232017 @default.
- W1937292223 countsByYear W19372922232019 @default.
- W1937292223 countsByYear W19372922232020 @default.
- W1937292223 countsByYear W19372922232022 @default.
- W1937292223 crossrefType "journal-article" @default.
- W1937292223 hasAuthorship W1937292223A5026731813 @default.
- W1937292223 hasAuthorship W1937292223A5032863911 @default.
- W1937292223 hasAuthorship W1937292223A5082944296 @default.
- W1937292223 hasConcept C121332964 @default.
- W1937292223 hasConcept C142424586 @default.
- W1937292223 hasConcept C143998085 @default.
- W1937292223 hasConcept C147483822 @default.
- W1937292223 hasConcept C203014093 @default.
- W1937292223 hasConcept C2778020697 @default.
- W1937292223 hasConcept C2778461978 @default.
- W1937292223 hasConcept C2778957590 @default.
- W1937292223 hasConcept C2779823535 @default.
- W1937292223 hasConcept C2909962599 @default.
- W1937292223 hasConcept C71924100 @default.
- W1937292223 hasConcept C87355193 @default.
- W1937292223 hasConceptScore W1937292223C121332964 @default.
- W1937292223 hasConceptScore W1937292223C142424586 @default.
- W1937292223 hasConceptScore W1937292223C143998085 @default.
- W1937292223 hasConceptScore W1937292223C147483822 @default.
- W1937292223 hasConceptScore W1937292223C203014093 @default.
- W1937292223 hasConceptScore W1937292223C2778020697 @default.
- W1937292223 hasConceptScore W1937292223C2778461978 @default.
- W1937292223 hasConceptScore W1937292223C2778957590 @default.
- W1937292223 hasConceptScore W1937292223C2779823535 @default.
- W1937292223 hasConceptScore W1937292223C2909962599 @default.
- W1937292223 hasConceptScore W1937292223C71924100 @default.
- W1937292223 hasConceptScore W1937292223C87355193 @default.
- W1937292223 hasIssue "12" @default.
- W1937292223 hasLocation W19372922231 @default.
- W1937292223 hasLocation W19372922232 @default.