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- W1937618586 abstract "Objective: High sensitivity C reactive protein (Hs-CRP) is an inflammatory marker known to be related to inflammation, infection, and cardiovascular disease. The aim of this study was to evaluate hs-CRP levels in serum of asthmatics and their relationship to pulmonary function tests, serum IgE levels, peripheral blood white blood cells (WBC) counts.Methods: The study groups were 108 patients with acute asthma and 93 healthy volunteers. The levels of hs-CRP of 108 patients with acute bronchial asthma and 93 non-asthmatic control subjects were measured. Spirometry, serum immunoglobulin-E (IgE) measurement, WBC and counts were done in all the patients and control groups.Results: Mean serum hs-CRP levels were significantly higher in patients with acute asthma compared with control (5.47±7.33 mg/l versus 1.46±1.89 mg/l, p<0.001). Among asthmatic patients, mean hs-CRP levels did not correlate with indices of pulmonary function (forced expiratory volume in one second/forced vital capacity and forced mid-expiratory flow), serum IgE level, eosinophil count and WBC.Conclusions: Increase in serum C-reactive protein levels measured by high-sensitivity assays may be associated with airflow obstruction in acute asthma, and may be useful as a sensitive marker and a diagnostic tool for detecting and monitoring airway inflammation in patients with acute asthma. In our study of patients with acute asthma, did not reveal any significant correlation between hsCRP and pulmonary function tests, total serum IgE, and peripheral blood white blood cells counts." @default.
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- W1937618586 date "2011-09-01" @default.
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- W1937618586 title "Evaluation of high-sensitivity C-reactive protein in acute asthma" @default.
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