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- W1937691813 abstract "It has been shown that dyspepsia can be associated with COPD and in some cases closely linked to COPD exacerbations. The association of dyspepsia with COPD severity (FEV1, respiratory failure) and medications is not well described. The aim of this study is to evaluate the prevalence of dyspepsia in a large canadian COPD cohort and to identify risk factors.We retrospectively reviewed files of 1247 COPD patients. We classified patients as dyspepsia-positive (D+: 513 patients or 41%) or dyspepsia-negative (D-: 734 patients or 59%). Mean age was similar in D+ and D- (71,6 y/o versus 70,2) and we found no difference in FEV1 (44,97% versus 45,07%, p>0,05). Dyspepsia was more frequent in female patients (54,4% versus 45,4%, p 1/year) was also associated with dyspepsia (80,3% versus 71,7%, p<0,001). Finally, dyspepsia was positively related to cardio-vascular and osteoporotic comorbidities (86,7% versus 68,4%, p< 0,001). No relation was found with medications use, notably inhaled corticosteroids.Conclusion: As reported by other publications, our retrospective study noted a high prevalence of dyspepsia in COPD patients and there was no relation with disease severity (expressed by the FEV1). Female sex, frequent acute exacerbations and comorbidities appear to be associated with dyspepsia. Surprisingly, we found a negative association with smoking status. Dyspepsia treatment consequences should now be addressed closely (QOL, exacerbations, FEV1 decline)." @default.
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- W1937691813 date "2011-09-01" @default.
- W1937691813 modified "2023-09-28" @default.
- W1937691813 title "Prevalence of dyspepsia in COPD patients: Experience in a large Canadian cohort" @default.
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