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- W193782606 abstract "The purpose of the trial Arrhythmias was to evaluate all the arrhythmic events in the control and treated patients by considering, in the latter, the chronological relation to the infusion of Streptokinase (SK). This was done in order to determine if the presence of arrhythmias was significantly greater in the treated patients, and if these arrhythmias could be considered as possible markers of reperfusion. 10 Centres participated by recording and evaluating all the hyperkinetic and hypokinetic arrhythmic events in the treated and control patients for an observation period of 2 hours including infusion of SK. The recording method used was computerised UCIC or Holter recording. The centre for data handling carried out storage and statistical elaboration of the data. The Lown and the Italian Modified Lown classifications were used. When appropriate, the statistical significance of observed differences was assessed with chi-square and t tests. 433 patients, 227 treated and 206 controls, were randomised. No statistically significant differences were observed between the two groups as regards the quantity and quality of the hyperkinetic or hypokinetic arrhythmias. On the contrary, on dividing the patients into two groups in accordance with the incidence of Hyperkinetic Ventricular Arrhythmias (HVA), more serious HVA were observed in the controls both in absolute value and in relation to those with better functional class, younger patients (less than 65 yrs.) and with multiple site infarct. The results of the search for arrhythmias which can be markers of reperfusion, show that the Slow Ventricular Tachycardia is the only arrhythmia which can be used as such." @default.
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- W193782606 date "1987-01-01" @default.
- W193782606 modified "2023-09-23" @default.
- W193782606 title "[The Italian Group for the Study of Streptokinase in Myocardial Infarct: Study of arrhythmias]." @default.
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