FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1938348729> ?p ?o ?g. }

• W1938348729 abstract "Protein-protein interaction (PPI) plays a crucial role in cellular biological processes and functions. The identification of protein interactions can lead to a better understanding of infection mechanisms and the development of many drugs and treatment. Several physiochemical experimental techniques have been applied to identify PPIs. However, these techniques are significantly time consuming and have covered only a small portion of the complete PPI networks. As a result, the need for computational techniques has increased to validate experimental results and to predict novel PPIs. In this work, we propose a domain identification approach for PPI prediction based only on Amino Acid (AA) sequence information. Domains are the structural and functional units of proteins and, therefore, proteins interact as a result of their interacting domains. We identify structural domains within proteins through integrating the amino acid compositional index in conjunction with physiochemical properties to construct a domain linker profile which is used to train a TreeBagger domain identification predictor. Once structural domains are identified in two protein sequences, we predict whether these two proteins interact or not by analyzing the interacting structural domains that they contain. The proposed approach was tested on a standard PPI dataset and showed considerable improvement over the existing PPI predictors." @default.
• W1938348729 created "2016-06-24" @default.
• W1938348729 creator A5028542466 @default.
• W1938348729 creator A5040640075 @default.
• W1938348729 date "2015-08-01" @default.
• W1938348729 modified "2023-09-25" @default.
• W1938348729 title "Novel domain identification approach for protein-protein interaction prediction" @default.
• W1938348729 cites W1486234769 @default.
• W1938348729 cites W1486817521 @default.
• W1938348729 cites W1512338554 @default.
• W1938348729 cites W1541754351 @default.
• W1938348729 cites W1546341583 @default.
• W1938348729 cites W1575542444 @default.
• W1938348729 cites W1970894966 @default.
• W1938348729 cites W1973508741 @default.
• W1938348729 cites W1982267716 @default.
• W1938348729 cites W1987582651 @default.
• W1938348729 cites W2005120335 @default.
• W1938348729 cites W2015556108 @default.
• W1938348729 cites W2026650804 @default.
• W1938348729 cites W2031616673 @default.
• W1938348729 cites W2039473152 @default.
• W1938348729 cites W2040411864 @default.
• W1938348729 cites W2044679407 @default.
• W1938348729 cites W2045131140 @default.
• W1938348729 cites W2047606947 @default.
• W1938348729 cites W2050135038 @default.
• W1938348729 cites W2052953199 @default.
• W1938348729 cites W2060568978 @default.
• W1938348729 cites W2065304353 @default.
• W1938348729 cites W2069891540 @default.
• W1938348729 cites W2074019887 @default.
• W1938348729 cites W2074231493 @default.
• W1938348729 cites W2084619201 @default.
• W1938348729 cites W2085963663 @default.
• W1938348729 cites W2087064593 @default.
• W1938348729 cites W2091710329 @default.
• W1938348729 cites W2099982459 @default.
• W1938348729 cites W2100530251 @default.
• W1938348729 cites W2104321823 @default.
• W1938348729 cites W2115906826 @default.
• W1938348729 cites W2116772258 @default.
• W1938348729 cites W2123957843 @default.
• W1938348729 cites W2126311442 @default.
• W1938348729 cites W2130687290 @default.
• W1938348729 cites W2132582966 @default.
• W1938348729 cites W2133138357 @default.
• W1938348729 cites W2133654213 @default.
• W1938348729 cites W2138929157 @default.
• W1938348729 cites W2141885858 @default.
• W1938348729 cites W2145427519 @default.
• W1938348729 cites W2147526198 @default.
• W1938348729 cites W2148356001 @default.
• W1938348729 cites W2152568394 @default.
• W1938348729 cites W2152705149 @default.
• W1938348729 cites W2160780826 @default.
• W1938348729 cites W2161701113 @default.
• W1938348729 cites W2166558964 @default.
• W1938348729 cites W2167851075 @default.
• W1938348729 cites W2170525533 @default.
• W1938348729 cites W3083668045 @default.
• W1938348729 cites W1884509322 @default.
• W1938348729 doi "https://doi.org/10.1109/cibcb.2015.7300340" @default.
• W1938348729 hasPublicationYear "2015" @default.
• W1938348729 type Work @default.
• W1938348729 sameAs 1938348729 @default.
• W1938348729 citedByCount "2" @default.
• W1938348729 countsByYear W19383487292016 @default.
• W1938348729 countsByYear W19383487292017 @default.
• W1938348729 crossrefType "proceedings-article" @default.
• W1938348729 hasAuthorship W1938348729A5028542466 @default.
• W1938348729 hasAuthorship W1938348729A5040640075 @default.
• W1938348729 hasConcept C104317684 @default.
• W1938348729 hasConcept C116834253 @default.
• W1938348729 hasConcept C11804247 @default.
• W1938348729 hasConcept C119857082 @default.
• W1938348729 hasConcept C124101348 @default.
• W1938348729 hasConcept C134306372 @default.
• W1938348729 hasConcept C144292202 @default.
• W1938348729 hasConcept C167625842 @default.
• W1938348729 hasConcept C199360897 @default.
• W1938348729 hasConcept C2780801425 @default.
• W1938348729 hasConcept C2994376932 @default.
• W1938348729 hasConcept C33923547 @default.
• W1938348729 hasConcept C36503486 @default.
• W1938348729 hasConcept C41008148 @default.
• W1938348729 hasConcept C47701112 @default.
• W1938348729 hasConcept C55493867 @default.
• W1938348729 hasConcept C59822182 @default.
• W1938348729 hasConcept C60644358 @default.
• W1938348729 hasConcept C69131567 @default.
• W1938348729 hasConcept C70721500 @default.
• W1938348729 hasConcept C86803240 @default.
• W1938348729 hasConceptScore W1938348729C104317684 @default.
• W1938348729 hasConceptScore W1938348729C116834253 @default.
• W1938348729 hasConceptScore W1938348729C11804247 @default.
• W1938348729 hasConceptScore W1938348729C119857082 @default.
• W1938348729 hasConceptScore W1938348729C124101348 @default.
• W1938348729 hasConceptScore W1938348729C134306372 @default.
• W1938348729 hasConceptScore W1938348729C144292202 @default.

• next