Matches in SemOpenAlex for { <https://semopenalex.org/work/W1938390162> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W1938390162 endingPage "35" @default.
- W1938390162 startingPage "30" @default.
- W1938390162 abstract "Traditional internal quality control schemes for qualitative infectious serology mostly rely on the use of commercial positive and negative quality control materials. However, with respect to the negative control, target values provided by the manufacturer are often poorly defined and non-commutability of the commercial materials further complicates correct interpretation of control results. An alternative quality control procedure using the median patient seronegative response is presented.Daily patient median responses were calculated for our Hepatitis B surface antigen, Hepatitis B core antibody, Hepatitis C antibody and HIV antigen/antibody test systems. Because of the low prevalence of these viruses in our area, most patient responses are negative. A minimum of 5 patient samples per day was required to generate a stable daily median. Control limits were calculated and daily patient medians were plotted against commercial quality control results.Commercial negative controls and daily patient medians mostly behaved in the same way. Nevertheless, for the Hepatitis B surface antigen test, patient medians frequently exceeded the calculated control limit in contrast to commercial quality controls. This confirms that target ranges provided by the manufacturer are not always adequate. Moreover, an important matrix-related interference occurred on our HIV antigen/antibody test system and correct interpretation was only possible using daily patient median results.Monitoring the daily patient median response can be a valuable alternative to traditional commercial negative quality control. It's easy to perform, cost-free, provides additional information with respect to matrix effects and allows for the establishment of well-defined control limits." @default.
- W1938390162 created "2016-06-24" @default.
- W1938390162 creator A5015811382 @default.
- W1938390162 creator A5069868837 @default.
- W1938390162 creator A5071480446 @default.
- W1938390162 creator A5083167145 @default.
- W1938390162 date "2015-11-01" @default.
- W1938390162 modified "2023-10-01" @default.
- W1938390162 title "Monitoring the patient response as an alternative to commercial negative quality control in infectious serology" @default.
- W1938390162 cites W1507985183 @default.
- W1938390162 cites W1522309498 @default.
- W1938390162 cites W2026863393 @default.
- W1938390162 cites W2050254088 @default.
- W1938390162 cites W2086969625 @default.
- W1938390162 cites W2166785990 @default.
- W1938390162 cites W2323086963 @default.
- W1938390162 cites W3150545588 @default.
- W1938390162 doi "https://doi.org/10.1016/j.jcv.2015.08.016" @default.
- W1938390162 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26363142" @default.
- W1938390162 hasPublicationYear "2015" @default.
- W1938390162 type Work @default.
- W1938390162 sameAs 1938390162 @default.
- W1938390162 citedByCount "0" @default.
- W1938390162 crossrefType "journal-article" @default.
- W1938390162 hasAuthorship W1938390162A5015811382 @default.
- W1938390162 hasAuthorship W1938390162A5069868837 @default.
- W1938390162 hasAuthorship W1938390162A5071480446 @default.
- W1938390162 hasAuthorship W1938390162A5083167145 @default.
- W1938390162 hasConcept C142724271 @default.
- W1938390162 hasConcept C159654299 @default.
- W1938390162 hasConcept C203014093 @default.
- W1938390162 hasConcept C2778618615 @default.
- W1938390162 hasConcept C45189115 @default.
- W1938390162 hasConcept C71924100 @default.
- W1938390162 hasConceptScore W1938390162C142724271 @default.
- W1938390162 hasConceptScore W1938390162C159654299 @default.
- W1938390162 hasConceptScore W1938390162C203014093 @default.
- W1938390162 hasConceptScore W1938390162C2778618615 @default.
- W1938390162 hasConceptScore W1938390162C45189115 @default.
- W1938390162 hasConceptScore W1938390162C71924100 @default.
- W1938390162 hasLocation W19383901621 @default.
- W1938390162 hasLocation W19383901622 @default.
- W1938390162 hasOpenAccess W1938390162 @default.
- W1938390162 hasPrimaryLocation W19383901621 @default.
- W1938390162 hasRelatedWork W1569996386 @default.
- W1938390162 hasRelatedWork W1924412450 @default.
- W1938390162 hasRelatedWork W2087632623 @default.
- W1938390162 hasRelatedWork W2245803233 @default.
- W1938390162 hasRelatedWork W2414984236 @default.
- W1938390162 hasRelatedWork W3117328029 @default.
- W1938390162 hasRelatedWork W3130176771 @default.
- W1938390162 hasRelatedWork W3206814153 @default.
- W1938390162 hasRelatedWork W4307032491 @default.
- W1938390162 hasRelatedWork W95735447 @default.
- W1938390162 hasVolume "72" @default.
- W1938390162 isParatext "false" @default.
- W1938390162 isRetracted "false" @default.
- W1938390162 magId "1938390162" @default.
- W1938390162 workType "article" @default.