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• W1938401877 abstract "// Xin Xu 1 , Yi Zhu 1 , Xiangyi Zheng 1 , Liping Xie 1 1 Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China Correspondence to: Liping Xie, e-mail: xielp@zju.edu.cn Keywords: alcohol, renal cell carcinoma, epidemiology, risk factor, meta-analysis Received: February 24, 2015      Accepted: April 15, 2015      Published: April 29, 2015 ABSTRACT Despite plenty of evidence supports an inverse association between alcohol drinking and risk of renal cell carcinoma (RCC), sex-specific and beverage-specific dose-response relationships have not been well established. We examined this association by performing a systematic review and meta-analysis of prospective studies. Studies were identified by comprehensively searching PubMed and EMBASE databases through February 21, 2015. Categorical and dose-response meta-analyses were conducted to identify the effects of alcohol on RCC. A total of eight publications (including seven cohort studies and one pooled analysis of 12 cohort studies) were eligible for this meta-analysis. Dose-response analysis showed that each 5 g/day increment of alcohol intake corresponded to a 5% decrease in risk of RCC for males and 9% for females. Alcohol intakes from wine, beer, and liquor were each associated with a reduced risk of RCC. When these associations were examined separately by gender, statistically significant inverse associations were restricted to alcohol from wine among females (RR = 0.82, 95% CI 0.73–0.91) and to alcohol from beer and from liquor among males (RR = 0.87, 95% CI 0.83–0.91 and RR = 0.95, 95% CI 0.92–0.99, respectively). In conclusion, there exist gender-specific and beverage-specific differences in the association between alcohol intake and RCC risk." @default.
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• W1938401877 date "2015-04-29" @default.
• W1938401877 modified "2023-10-14" @default.
• W1938401877 title "Does beer, wine or liquor consumption correlate with the risk of renal cell carcinoma? A dose-response meta-analysis of prospective cohort studies" @default.
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• W1938401877 doi "https://doi.org/10.18632/oncotarget.3749" @default.
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