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- W193844952 abstract "PtK1 cells enter prophase and complete mitosis at 24-25 degrees C but are inhibited from entering prophase at 20-21 degrees C. Cells which have progressed up to midprophase at 24-37 degrees C return to interphase when cooled to 20-21 degrees C, but those in late prophase complete a normal, although prolonged mitosis. If prophase cells which have reverted to interphase at 20-21 degrees C are incubated at 24-37 degrees C they reenter prophase and complete mitosis. This temperature-induced prophase-interphase-prophase transition can be repeated several times on the same cell. At 24-25 degrees C the process of spindle formation (i.e. prometaphase to the initiation of anaphase) encompasses approximately 75% of the total mitotic interval, with a duration of 8-12 h, compared to about 50% of the mitotic interval and a duration of 0.5 to 1.0 h at 37 degrees C." @default.
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- W193844952 date "1981-06-01" @default.
- W193844952 modified "2023-09-24" @default.
- W193844952 title "Effect of hypothermia (20–25°C) on mitosis in PtK1 cells" @default.
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- W193844952 doi "https://doi.org/10.1016/s0309-1651(81)80007-0" @default.
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