Matches in SemOpenAlex for { <https://semopenalex.org/work/W1938539934> ?p ?o ?g. }
- W1938539934 endingPage "241" @default.
- W1938539934 startingPage "235" @default.
- W1938539934 abstract "This multicentre open-label trial examined the efficacy and safety of the traditional Japanese medicine, or Kampo medicine, yokukansan (YKS), for behavioural and psychological symptoms of dementia (BPSD) in patients with dementia with Lewy bodies.Sixty-three dementia with Lewy bodies patients with probable BPSD (M:W, 30:33; mean age, 78.2±5.8 years) were enrolled and treated with YKS for 4 weeks.Significant improvements in Neuropsychiatric Inventory scores (mean decrease, 12.5 points; P<0.001) and Zarit Burden Interview-Japanese edition tests (mean decrease, 3.6 points; P=0.024) were observed. In patients who consented to an assessment after 2 weeks of treatment, a time-dependent significant improvement was observed in the Neuropsychiatric Inventory score (n=23; mean decrease, 14.4; P<0.001), each subscale, including delusions and hallucinations, the Zarit Burden Interview-Japanese edition (n=22; mean decrease, 8.2; P<0.01) and the behavioural pathology in Alzheimer's disease insomnia subscale. The Mini-Mental State Examination and the Disability Assessment for Dementia (DAD) showed no significant change. Adverse events were observed in 11 (18%) patients. Three patients (5%) discontinued YKS due to adverse reactions, namely, spasticity and exacerbation of BPSD, edema, and nausea. Hypokalaemia (<3.5 mEq/L) was present in four patients (6%) at the study endpoint. Worsening of extrapyramidal symptoms was not observed.YKS improved BPSD in dementia with Lewy bodies patients and caregiver burden scores without deterioration in cognitive function. YKS is useful for the treatment of delusions and hallucinations in BPSD." @default.
- W1938539934 created "2016-06-24" @default.
- W1938539934 creator A5002514266 @default.
- W1938539934 creator A5004523187 @default.
- W1938539934 creator A5014649936 @default.
- W1938539934 creator A5017952998 @default.
- W1938539934 creator A5018274235 @default.
- W1938539934 creator A5022999645 @default.
- W1938539934 creator A5024364260 @default.
- W1938539934 creator A5028331779 @default.
- W1938539934 creator A5030666334 @default.
- W1938539934 creator A5033709321 @default.
- W1938539934 creator A5034823575 @default.
- W1938539934 creator A5047638458 @default.
- W1938539934 creator A5047776373 @default.
- W1938539934 creator A5056491345 @default.
- W1938539934 creator A5057482485 @default.
- W1938539934 creator A5060124541 @default.
- W1938539934 creator A5071391669 @default.
- W1938539934 creator A5073708221 @default.
- W1938539934 creator A5082649012 @default.
- W1938539934 date "2012-12-01" @default.
- W1938539934 modified "2023-10-09" @default.
- W1938539934 title "Improvement in delusions and hallucinations in patients with dementia with Lewy bodies upon administration of yokukansan, a traditional Japanese medicine" @default.
- W1938539934 cites W1524211283 @default.
- W1938539934 cites W1688235741 @default.
- W1938539934 cites W1847168837 @default.
- W1938539934 cites W1965215445 @default.
- W1938539934 cites W1973355565 @default.
- W1938539934 cites W1974886457 @default.
- W1938539934 cites W1977505230 @default.
- W1938539934 cites W1979757369 @default.
- W1938539934 cites W1981270038 @default.
- W1938539934 cites W1993818042 @default.
- W1938539934 cites W1994506529 @default.
- W1938539934 cites W2004335391 @default.
- W1938539934 cites W2007063636 @default.
- W1938539934 cites W2043697763 @default.
- W1938539934 cites W2051106048 @default.
- W1938539934 cites W2056252291 @default.
- W1938539934 cites W2069826333 @default.
- W1938539934 cites W2071937138 @default.
- W1938539934 cites W2074085250 @default.
- W1938539934 cites W2077398422 @default.
- W1938539934 cites W2078246300 @default.
- W1938539934 cites W2087541289 @default.
- W1938539934 cites W2089384719 @default.
- W1938539934 cites W2102343148 @default.
- W1938539934 cites W2102572922 @default.
- W1938539934 cites W2111963393 @default.
- W1938539934 cites W2123056519 @default.
- W1938539934 cites W2148332448 @default.
- W1938539934 cites W2163003927 @default.
- W1938539934 cites W4300450225 @default.
- W1938539934 doi "https://doi.org/10.1111/j.1479-8301.2012.00413.x" @default.
- W1938539934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23279145" @default.
- W1938539934 hasPublicationYear "2012" @default.
- W1938539934 type Work @default.
- W1938539934 sameAs 1938539934 @default.
- W1938539934 citedByCount "44" @default.
- W1938539934 countsByYear W19385399342012 @default.
- W1938539934 countsByYear W19385399342013 @default.
- W1938539934 countsByYear W19385399342014 @default.
- W1938539934 countsByYear W19385399342015 @default.
- W1938539934 countsByYear W19385399342016 @default.
- W1938539934 countsByYear W19385399342017 @default.
- W1938539934 countsByYear W19385399342018 @default.
- W1938539934 countsByYear W19385399342019 @default.
- W1938539934 countsByYear W19385399342021 @default.
- W1938539934 countsByYear W19385399342022 @default.
- W1938539934 countsByYear W19385399342023 @default.
- W1938539934 crossrefType "journal-article" @default.
- W1938539934 hasAuthorship W1938539934A5002514266 @default.
- W1938539934 hasAuthorship W1938539934A5004523187 @default.
- W1938539934 hasAuthorship W1938539934A5014649936 @default.
- W1938539934 hasAuthorship W1938539934A5017952998 @default.
- W1938539934 hasAuthorship W1938539934A5018274235 @default.
- W1938539934 hasAuthorship W1938539934A5022999645 @default.
- W1938539934 hasAuthorship W1938539934A5024364260 @default.
- W1938539934 hasAuthorship W1938539934A5028331779 @default.
- W1938539934 hasAuthorship W1938539934A5030666334 @default.
- W1938539934 hasAuthorship W1938539934A5033709321 @default.
- W1938539934 hasAuthorship W1938539934A5034823575 @default.
- W1938539934 hasAuthorship W1938539934A5047638458 @default.
- W1938539934 hasAuthorship W1938539934A5047776373 @default.
- W1938539934 hasAuthorship W1938539934A5056491345 @default.
- W1938539934 hasAuthorship W1938539934A5057482485 @default.
- W1938539934 hasAuthorship W1938539934A5060124541 @default.
- W1938539934 hasAuthorship W1938539934A5071391669 @default.
- W1938539934 hasAuthorship W1938539934A5073708221 @default.
- W1938539934 hasAuthorship W1938539934A5082649012 @default.
- W1938539934 hasBestOaLocation W19385399341 @default.
- W1938539934 hasConcept C118552586 @default.
- W1938539934 hasConcept C126322002 @default.
- W1938539934 hasConcept C15744967 @default.
- W1938539934 hasConcept C197934379 @default.
- W1938539934 hasConcept C2776525014 @default.
- W1938539934 hasConcept C2777014857 @default.