Matches in SemOpenAlex for { <https://semopenalex.org/work/W1938949028> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1938949028 endingPage "1296" @default.
- W1938949028 startingPage "1291" @default.
- W1938949028 abstract "In view of evidence that nutritional status of iron and vitamin A may affect the other nutrient's metabolism, we used model-based compartmental analysis to examine effects of iron deficiency on whole-body vitamin A dynamics in rats. Weanling male Sprague-Dawley rats were fed the AIN93G diet with 2.5 nmol retinyl palmitate/g and either 45 [control (CN)] or 4 microg/g Fe [iron-deficient (ID)] for 8 wk. ID rats consumed food ad libitum; CN rats were food-restricted so that their body weights were the same as ID rats. Two rats/group were killed; liver vitamin A was determined and used for vitamin A balance calculations. [(3)H]Retinol-labeled plasma was administered intravenously to remaining rats, and 27 serial blood samples were collected for 7 wk. At killing, plasma vitamin A was 0.52+/-0.12 (ID, n = 5) vs. 1.34+/-0.12 micromol/L (CN, n = 6; P<0.001), and liver vitamin A was 809+/-94 (ID) vs. 112+/-24 nmol (CN, P<0.001). Plasma tracer data were fit to a three- or four-compartment model using the Simulation, Analysis and Modeling computer program and kinetic parameters were calculated. Vitamin A transfer rate between the retinyl ester storage pool [14+/-3 (ID) vs. 24+/-4 nmol/d (CN), P<0.05] and plasma was lower in ID rats. Vitamin A remained longer in the body [44+/-11 (ID) vs. 22+/-3 d (CN), P<0.05]. Adjusted mean disposal rate was lower in ID (10.0) than CN rats (19.9 nmol/d), as was estimated vitamin A absorption efficiency [58% (ID) vs. 76% (CN)]. Our results suggest that iron deficiency inhibits mobilization of vitamin A stores and may decrease the absorption and irreversible utilization of vitamin A." @default.
- W1938949028 created "2016-06-24" @default.
- W1938949028 creator A5031233296 @default.
- W1938949028 creator A5040008947 @default.
- W1938949028 creator A5044133666 @default.
- W1938949028 creator A5074748805 @default.
- W1938949028 date "2000-05-01" @default.
- W1938949028 modified "2023-10-12" @default.
- W1938949028 title "Kinetic Analysis Shows That Iron Deficiency Decreases Liver Vitamin A Mobilization in Rats" @default.
- W1938949028 cites W1519642514 @default.
- W1938949028 cites W1565218033 @default.
- W1938949028 cites W1753544142 @default.
- W1938949028 cites W1821774545 @default.
- W1938949028 cites W1831301545 @default.
- W1938949028 cites W1835909554 @default.
- W1938949028 cites W1838633818 @default.
- W1938949028 cites W1895592204 @default.
- W1938949028 cites W1945371044 @default.
- W1938949028 cites W1958289030 @default.
- W1938949028 cites W1958595820 @default.
- W1938949028 cites W1967650076 @default.
- W1938949028 cites W2005017968 @default.
- W1938949028 cites W2098574972 @default.
- W1938949028 cites W2112406962 @default.
- W1938949028 cites W2153553663 @default.
- W1938949028 cites W2179538806 @default.
- W1938949028 cites W2312735235 @default.
- W1938949028 cites W2331113441 @default.
- W1938949028 cites W2412116072 @default.
- W1938949028 cites W2413344286 @default.
- W1938949028 doi "https://doi.org/10.1093/jn/130.5.1291" @default.
- W1938949028 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10801932" @default.
- W1938949028 hasPublicationYear "2000" @default.
- W1938949028 type Work @default.
- W1938949028 sameAs 1938949028 @default.
- W1938949028 citedByCount "78" @default.
- W1938949028 countsByYear W19389490282012 @default.
- W1938949028 countsByYear W19389490282013 @default.
- W1938949028 countsByYear W19389490282014 @default.
- W1938949028 countsByYear W19389490282015 @default.
- W1938949028 countsByYear W19389490282016 @default.
- W1938949028 countsByYear W19389490282017 @default.
- W1938949028 countsByYear W19389490282018 @default.
- W1938949028 countsByYear W19389490282019 @default.
- W1938949028 countsByYear W19389490282020 @default.
- W1938949028 countsByYear W19389490282022 @default.
- W1938949028 crossrefType "journal-article" @default.
- W1938949028 hasAuthorship W1938949028A5031233296 @default.
- W1938949028 hasAuthorship W1938949028A5040008947 @default.
- W1938949028 hasAuthorship W1938949028A5044133666 @default.
- W1938949028 hasAuthorship W1938949028A5074748805 @default.
- W1938949028 hasBestOaLocation W19389490281 @default.
- W1938949028 hasConcept C126322002 @default.
- W1938949028 hasConcept C134018914 @default.
- W1938949028 hasConcept C14522933 @default.
- W1938949028 hasConcept C178790620 @default.
- W1938949028 hasConcept C185592680 @default.
- W1938949028 hasConcept C2776940978 @default.
- W1938949028 hasConcept C2777326149 @default.
- W1938949028 hasConcept C2778129702 @default.
- W1938949028 hasConcept C2778433245 @default.
- W1938949028 hasConcept C2779573558 @default.
- W1938949028 hasConcept C62231903 @default.
- W1938949028 hasConcept C71924100 @default.
- W1938949028 hasConcept C86803240 @default.
- W1938949028 hasConceptScore W1938949028C126322002 @default.
- W1938949028 hasConceptScore W1938949028C134018914 @default.
- W1938949028 hasConceptScore W1938949028C14522933 @default.
- W1938949028 hasConceptScore W1938949028C178790620 @default.
- W1938949028 hasConceptScore W1938949028C185592680 @default.
- W1938949028 hasConceptScore W1938949028C2776940978 @default.
- W1938949028 hasConceptScore W1938949028C2777326149 @default.
- W1938949028 hasConceptScore W1938949028C2778129702 @default.
- W1938949028 hasConceptScore W1938949028C2778433245 @default.
- W1938949028 hasConceptScore W1938949028C2779573558 @default.
- W1938949028 hasConceptScore W1938949028C62231903 @default.
- W1938949028 hasConceptScore W1938949028C71924100 @default.
- W1938949028 hasConceptScore W1938949028C86803240 @default.
- W1938949028 hasIssue "5" @default.
- W1938949028 hasLocation W19389490281 @default.
- W1938949028 hasLocation W19389490282 @default.
- W1938949028 hasOpenAccess W1938949028 @default.
- W1938949028 hasPrimaryLocation W19389490281 @default.
- W1938949028 hasRelatedWork W1895354212 @default.
- W1938949028 hasRelatedWork W1938949028 @default.
- W1938949028 hasRelatedWork W1987008782 @default.
- W1938949028 hasRelatedWork W1998601765 @default.
- W1938949028 hasRelatedWork W2017450385 @default.
- W1938949028 hasRelatedWork W2042871724 @default.
- W1938949028 hasRelatedWork W2081364625 @default.
- W1938949028 hasRelatedWork W2411464648 @default.
- W1938949028 hasRelatedWork W2465700402 @default.
- W1938949028 hasRelatedWork W2969288197 @default.
- W1938949028 hasVolume "130" @default.
- W1938949028 isParatext "false" @default.
- W1938949028 isRetracted "false" @default.
- W1938949028 magId "1938949028" @default.
- W1938949028 workType "article" @default.