FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1938998087> ?p ?o ?g. }

• W1938998087 endingPage "2165" @default.
• W1938998087 startingPage "2153" @default.
• W1938998087 abstract "To make delivery improvements via delivery systems for 6-(4-morpholino-3-(trifluoromethyl)phenyl)pyridazin-3(2H)-one (DZO) - a model compound of hydrophobic antitumor candidate pyridazinone derivatives.Methoxy poly(ethylene glycol)-poly(D,L-lactide) (MPEG-PDLLA) micelle was employed as a vector, and DZO was encapsulated in. The DZO-loaded micelles were characterized in detail and its cytotoxicity, maximum tolerated dose (MTD) and pharmacokinetic experiments were done. In vivo anticancer activity was studied through a subcutaneous 4T1 tumor model.Compared with free DZO, the DZO-loaded micelles possessed a sustained release property, an improved MTD, better pharmacokinetic parameters and an enhanced antitumor activity for subcutaneous 4T1 model in vivo.An effective injectable delivery system for DZO was developed successfully." @default.
• W1938998087 created "2016-06-24" @default.
• W1938998087 creator A5007409515 @default.
• W1938998087 creator A5012152127 @default.
• W1938998087 creator A5028960532 @default.
• W1938998087 creator A5040621231 @default.
• W1938998087 creator A5049215942 @default.
• W1938998087 creator A5051905815 @default.
• W1938998087 creator A5063515570 @default.
• W1938998087 creator A5069190300 @default.
• W1938998087 date "2015-07-01" @default.
• W1938998087 modified "2023-10-18" @default.
• W1938998087 title "An efficient injectable formulation with block copolymer micelles for hydrophobic antitumor candidate-pyridazinone derivatives" @default.
• W1938998087 cites W1969964192 @default.
• W1938998087 cites W1989143971 @default.
• W1938998087 cites W1989195046 @default.
• W1938998087 cites W1989220118 @default.
• W1938998087 cites W1990750564 @default.
• W1938998087 cites W1996400613 @default.
• W1938998087 cites W1997218466 @default.
• W1938998087 cites W1998269448 @default.
• W1938998087 cites W2002516695 @default.
• W1938998087 cites W2006428933 @default.
• W1938998087 cites W2012867962 @default.
• W1938998087 cites W2014941970 @default.
• W1938998087 cites W2017865089 @default.
• W1938998087 cites W2021876818 @default.
• W1938998087 cites W2021917597 @default.
• W1938998087 cites W2040500601 @default.
• W1938998087 cites W2042162667 @default.
• W1938998087 cites W2050296608 @default.
• W1938998087 cites W2054475291 @default.
• W1938998087 cites W2065601487 @default.
• W1938998087 cites W2065698339 @default.
• W1938998087 cites W2067184525 @default.
• W1938998087 cites W2069506489 @default.
• W1938998087 cites W2080270710 @default.
• W1938998087 cites W2083244872 @default.
• W1938998087 cites W2085131775 @default.
• W1938998087 cites W2104244948 @default.
• W1938998087 cites W2123255383 @default.
• W1938998087 cites W2124356270 @default.
• W1938998087 cites W2134505027 @default.
• W1938998087 cites W2148706833 @default.
• W1938998087 cites W2168661387 @default.
• W1938998087 cites W2319995869 @default.
• W1938998087 cites W2331270961 @default.
• W1938998087 cites W2952855503 @default.
• W1938998087 cites W3103982839 @default.
• W1938998087 cites W4231616200 @default.
• W1938998087 doi "https://doi.org/10.2217/nnm.15.66" @default.
• W1938998087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26214355" @default.
• W1938998087 hasPublicationYear "2015" @default.
• W1938998087 type Work @default.
• W1938998087 sameAs 1938998087 @default.
• W1938998087 citedByCount "6" @default.
• W1938998087 countsByYear W19389980872016 @default.
• W1938998087 countsByYear W19389980872017 @default.
• W1938998087 countsByYear W19389980872018 @default.
• W1938998087 countsByYear W19389980872019 @default.
• W1938998087 countsByYear W19389980872022 @default.
• W1938998087 crossrefType "journal-article" @default.
• W1938998087 hasAuthorship W1938998087A5007409515 @default.
• W1938998087 hasAuthorship W1938998087A5012152127 @default.
• W1938998087 hasAuthorship W1938998087A5028960532 @default.
• W1938998087 hasAuthorship W1938998087A5040621231 @default.
• W1938998087 hasAuthorship W1938998087A5049215942 @default.
• W1938998087 hasAuthorship W1938998087A5051905815 @default.
• W1938998087 hasAuthorship W1938998087A5063515570 @default.
• W1938998087 hasAuthorship W1938998087A5069190300 @default.
• W1938998087 hasConcept C109316439 @default.
• W1938998087 hasConcept C11268172 @default.
• W1938998087 hasConcept C112705442 @default.
• W1938998087 hasConcept C150903083 @default.
• W1938998087 hasConcept C15920480 @default.
• W1938998087 hasConcept C178790620 @default.
• W1938998087 hasConcept C184651966 @default.
• W1938998087 hasConcept C185592680 @default.
• W1938998087 hasConcept C202751555 @default.
• W1938998087 hasConcept C207001950 @default.
• W1938998087 hasConcept C21951064 @default.
• W1938998087 hasConcept C2777516009 @default.
• W1938998087 hasConcept C521977710 @default.
• W1938998087 hasConcept C55493867 @default.
• W1938998087 hasConcept C71924100 @default.
• W1938998087 hasConcept C86803240 @default.
• W1938998087 hasConcept C98274493 @default.
• W1938998087 hasConceptScore W1938998087C109316439 @default.
• W1938998087 hasConceptScore W1938998087C11268172 @default.
• W1938998087 hasConceptScore W1938998087C112705442 @default.
• W1938998087 hasConceptScore W1938998087C150903083 @default.
• W1938998087 hasConceptScore W1938998087C15920480 @default.
• W1938998087 hasConceptScore W1938998087C178790620 @default.
• W1938998087 hasConceptScore W1938998087C184651966 @default.
• W1938998087 hasConceptScore W1938998087C185592680 @default.
• W1938998087 hasConceptScore W1938998087C202751555 @default.
• W1938998087 hasConceptScore W1938998087C207001950 @default.
• W1938998087 hasConceptScore W1938998087C21951064 @default.

• next