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• W1939220970 abstract "In the present study we describe the in vitro pharmacological characterization of the nociceptin/orphanin FQ (N/OFQ) receptor (NOP) ligand Ac-RYYRWK-NH2 and the synthesis and biological evaluation of 13 Trp5 substituted Ac-RYYRWK-NH2 analogs. Results indicate that Ac-RYYRWK-NH2 behaves as a highly potent and selective partial agonist at the NOP receptors and that the whole indole moiety of the Trp5 side chain is not required, being a phenyl-ethyl side chain already sufficient for maintaining high potency." @default.
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• W1939220970 date "2005-07-01" @default.
• W1939220970 modified "2023-10-18" @default.
• W1939220970 title "Tryptophan replacement in the nociceptin/orphanin FQ receptor ligand Ac-RYYRWK-NH2" @default.
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• W1939220970 doi "https://doi.org/10.1111/j.1399-3011.2005.00272.x" @default.
• W1939220970 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15946194" @default.
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