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- W1939242577 endingPage "407" @default.
- W1939242577 startingPage "397" @default.
- W1939242577 abstract "Abstract The adhesive interactions of leukocytes with basement membrane components and other extracellular matrix (ECM) proteins are mediated largely by the integrin family of receptors. These interactions can be regulated by various effector molecules including chemokines, growth factors, and other cell surface proteins by a mechanism termed inside-out signaling of integrin function. On engagement by their ligands, integrins activate a wide range of signaling pathways that regulate a broad array of leukocyte functions such as chemotaxis, cytokine responsiveness, phagocytosis, and gene expression. This review highlights recent advances in the understanding of integrin signaling in leukocytes with an emphasis on our own work on the α6β1 integrin, the major laminin receptor expressed by these cells." @default.
- W1939242577 created "2016-06-24" @default.
- W1939242577 creator A5010527699 @default.
- W1939242577 creator A5023136222 @default.
- W1939242577 creator A5084297561 @default.
- W1939242577 date "1997-04-01" @default.
- W1939242577 modified "2023-09-25" @default.
- W1939242577 title "Integrin signaling in leukocytes: lessons from the α6β1 integrin" @default.
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