FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1939397978> ?p ?o ?g. }

• W1939397978 endingPage "1199" @default.
• W1939397978 startingPage "1192" @default.
• W1939397978 abstract "We have recently showed that the weighted contact number profiles (or the packing density profiles) of proteins are well correlated with those of the corresponding sequence conservation profiles. The results suggest that a protein structure may contain sufficient information about sequence conservation comparable to that derived from multiple homologous sequences. However, there are ambiguities concerning how to compute the packing density of the subunit of a protein complex. For the subunits of a complex, there are different ways to compute its packing density--one including the packing contributions of the other subunits and the other one excluding their contributions. Here we selected two sets of enzyme complexes. Set A contains complexes with the active sites comprising residues from multiple subunits, while set B contains those with the active sites residing on single subunits. In Set A, if the packing density profile of a subunit is computed considering the contributions of the other subunits of the complex, it will agree better with the sequence conservation profile. But in Set B the situations are reversed. The results may be due to the stronger functional and structural constraints on the evolution processes on the complexes of Set A than those of Set B to maintain the enzymatic functions of the complexes. The comparison of the packing density and the sequence conservation profiles may provide a simple yet potentially useful way to understanding the structural and evolutionary couplings between the subunits of protein complexes." @default.
• W1939397978 created "2016-06-24" @default.
• W1939397978 creator A5024631735 @default.
• W1939397978 creator A5041730336 @default.
• W1939397978 creator A5041832023 @default.
• W1939397978 creator A5062301602 @default.
• W1939397978 date "2013-04-10" @default.
• W1939397978 modified "2023-10-06" @default.
• W1939397978 title "On the relationship between the sequence conservation and the packing density profiles of the protein complexes" @default.
• W1939397978 cites W1861776684 @default.
• W1939397978 cites W1913874700 @default.
• W1939397978 cites W1964640688 @default.
• W1939397978 cites W1987749411 @default.
• W1939397978 cites W2008708467 @default.
• W1939397978 cites W2012610559 @default.
• W1939397978 cites W2024138709 @default.
• W1939397978 cites W2029118067 @default.
• W1939397978 cites W2030277519 @default.
• W1939397978 cites W2044772240 @default.
• W1939397978 cites W2045501270 @default.
• W1939397978 cites W2071167128 @default.
• W1939397978 cites W2103040549 @default.
• W1939397978 cites W2116099439 @default.
• W1939397978 cites W2116743097 @default.
• W1939397978 cites W2141627824 @default.
• W1939397978 cites W2156125289 @default.
• W1939397978 cites W2158714788 @default.
• W1939397978 cites W2168621448 @default.
• W1939397978 cites W2171190723 @default.
• W1939397978 cites W24553703 @default.
• W1939397978 cites W2016745351 @default.
• W1939397978 doi "https://doi.org/10.1002/prot.24268" @default.
• W1939397978 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23408640" @default.
• W1939397978 hasPublicationYear "2013" @default.
• W1939397978 type Work @default.
• W1939397978 sameAs 1939397978 @default.
• W1939397978 citedByCount "11" @default.
• W1939397978 countsByYear W19393979782014 @default.
• W1939397978 countsByYear W19393979782015 @default.
• W1939397978 countsByYear W19393979782016 @default.
• W1939397978 countsByYear W19393979782017 @default.
• W1939397978 countsByYear W19393979782018 @default.
• W1939397978 countsByYear W19393979782023 @default.
• W1939397978 crossrefType "journal-article" @default.
• W1939397978 hasAuthorship W1939397978A5024631735 @default.
• W1939397978 hasAuthorship W1939397978A5041730336 @default.
• W1939397978 hasAuthorship W1939397978A5041832023 @default.
• W1939397978 hasAuthorship W1939397978A5062301602 @default.
• W1939397978 hasConcept C10010492 @default.
• W1939397978 hasConcept C104292427 @default.
• W1939397978 hasConcept C104317684 @default.
• W1939397978 hasConcept C167625842 @default.
• W1939397978 hasConcept C177264268 @default.
• W1939397978 hasConcept C178180057 @default.
• W1939397978 hasConcept C183893376 @default.
• W1939397978 hasConcept C185592680 @default.
• W1939397978 hasConcept C199216141 @default.
• W1939397978 hasConcept C199360897 @default.
• W1939397978 hasConcept C2524010 @default.
• W1939397978 hasConcept C2778112365 @default.
• W1939397978 hasConcept C33923547 @default.
• W1939397978 hasConcept C41008148 @default.
• W1939397978 hasConcept C47701112 @default.
• W1939397978 hasConcept C54355233 @default.
• W1939397978 hasConcept C55493867 @default.
• W1939397978 hasConcept C70721500 @default.
• W1939397978 hasConcept C86803240 @default.
• W1939397978 hasConceptScore W1939397978C10010492 @default.
• W1939397978 hasConceptScore W1939397978C104292427 @default.
• W1939397978 hasConceptScore W1939397978C104317684 @default.
• W1939397978 hasConceptScore W1939397978C167625842 @default.
• W1939397978 hasConceptScore W1939397978C177264268 @default.
• W1939397978 hasConceptScore W1939397978C178180057 @default.
• W1939397978 hasConceptScore W1939397978C183893376 @default.
• W1939397978 hasConceptScore W1939397978C185592680 @default.
• W1939397978 hasConceptScore W1939397978C199216141 @default.
• W1939397978 hasConceptScore W1939397978C199360897 @default.
• W1939397978 hasConceptScore W1939397978C2524010 @default.
• W1939397978 hasConceptScore W1939397978C2778112365 @default.
• W1939397978 hasConceptScore W1939397978C33923547 @default.
• W1939397978 hasConceptScore W1939397978C41008148 @default.
• W1939397978 hasConceptScore W1939397978C47701112 @default.
• W1939397978 hasConceptScore W1939397978C54355233 @default.
• W1939397978 hasConceptScore W1939397978C55493867 @default.
• W1939397978 hasConceptScore W1939397978C70721500 @default.
• W1939397978 hasConceptScore W1939397978C86803240 @default.
• W1939397978 hasIssue "7" @default.
• W1939397978 hasLocation W19393979781 @default.
• W1939397978 hasLocation W19393979782 @default.
• W1939397978 hasOpenAccess W1939397978 @default.
• W1939397978 hasPrimaryLocation W19393979781 @default.
• W1939397978 hasRelatedWork W1858351564 @default.
• W1939397978 hasRelatedWork W1939397978 @default.
• W1939397978 hasRelatedWork W1975591133 @default.
• W1939397978 hasRelatedWork W1985666157 @default.
• W1939397978 hasRelatedWork W2044467472 @default.
• W1939397978 hasRelatedWork W2103040549 @default.
• W1939397978 hasRelatedWork W2144482528 @default.

• next