FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1939496645> ?p ?o ?g. }

• W1939496645 endingPage "1143" @default.
• W1939496645 startingPage "1137" @default.
• W1939496645 abstract "The effects of intramuscularly and orally administered medroxyprogesterone acetate on cytochrome P450 3A4 (CYP3A4) activity were investigated in twelve postmenopausal women in a randomized, crossover study. Unbound prednisolone clearance and the erythromycin breath test were used as markers of CYP3A4 activity. After 2 months of intramuscular progestin therapy, unbound prednisolone clearance increased by 25% in five of six subjects. Similarly, after intramuscular progestin therapy, results from the erythromycin breath test showed a 23% mean increase in CYP3A4 activity. In contrast, 2 months of oral progestin therapy had no effect on prednisolone pharmacokinetics or erythromycin metabolism. These results suggest that parenterally but not orally administered progestins may induce or activate the CYP3A4 enzyme system, leading to an increased metabolism of many CYP3A4 substrates." @default.
• W1939496645 created "2016-06-24" @default.
• W1939496645 creator A5012228576 @default.
• W1939496645 creator A5021182104 @default.
• W1939496645 creator A5054733730 @default.
• W1939496645 creator A5075960682 @default.
• W1939496645 date "1998-12-01" @default.
• W1939496645 modified "2023-10-18" @default.
• W1939496645 title "Preliminary Evaluation of Progestins as Inducers of Cytochrome P450 3A4 Activity in Postmenopausal Women" @default.
• W1939496645 cites W1520746198 @default.
• W1939496645 cites W1952999084 @default.
• W1939496645 cites W1965799818 @default.
• W1939496645 cites W1967752524 @default.
• W1939496645 cites W1972280475 @default.
• W1939496645 cites W1972387119 @default.
• W1939496645 cites W1986245831 @default.
• W1939496645 cites W1986538569 @default.
• W1939496645 cites W1989740023 @default.
• W1939496645 cites W1992611590 @default.
• W1939496645 cites W1993263798 @default.
• W1939496645 cites W1998758469 @default.
• W1939496645 cites W2002409168 @default.
• W1939496645 cites W2004219727 @default.
• W1939496645 cites W2010500561 @default.
• W1939496645 cites W2018522485 @default.
• W1939496645 cites W2020738884 @default.
• W1939496645 cites W2036520108 @default.
• W1939496645 cites W2048033938 @default.
• W1939496645 cites W2051175552 @default.
• W1939496645 cites W2066564684 @default.
• W1939496645 cites W2067161567 @default.
• W1939496645 cites W2074071877 @default.
• W1939496645 cites W2076946520 @default.
• W1939496645 cites W2079538757 @default.
• W1939496645 cites W2083675642 @default.
• W1939496645 cites W2083983666 @default.
• W1939496645 cites W2089242741 @default.
• W1939496645 cites W2090600824 @default.
• W1939496645 cites W2098008357 @default.
• W1939496645 cites W2107751156 @default.
• W1939496645 cites W2142869955 @default.
• W1939496645 cites W2154697918 @default.
• W1939496645 cites W2162498294 @default.
• W1939496645 cites W35328526 @default.
• W1939496645 cites W56240973 @default.
• W1939496645 doi "https://doi.org/10.1177/009127009803801208" @default.
• W1939496645 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11301566" @default.
• W1939496645 hasPublicationYear "1998" @default.
• W1939496645 type Work @default.
• W1939496645 sameAs 1939496645 @default.
• W1939496645 citedByCount "17" @default.
• W1939496645 countsByYear W19394966452012 @default.
• W1939496645 countsByYear W19394966452013 @default.
• W1939496645 countsByYear W19394966452015 @default.
• W1939496645 countsByYear W19394966452016 @default.
• W1939496645 crossrefType "journal-article" @default.
• W1939496645 hasAuthorship W1939496645A5012228576 @default.
• W1939496645 hasAuthorship W1939496645A5021182104 @default.
• W1939496645 hasAuthorship W1939496645A5054733730 @default.
• W1939496645 hasAuthorship W1939496645A5075960682 @default.
• W1939496645 hasConcept C109650736 @default.
• W1939496645 hasConcept C112705442 @default.
• W1939496645 hasConcept C126322002 @default.
• W1939496645 hasConcept C134018914 @default.
• W1939496645 hasConcept C142724271 @default.
• W1939496645 hasConcept C185592680 @default.
• W1939496645 hasConcept C204787440 @default.
• W1939496645 hasConcept C27081682 @default.
• W1939496645 hasConcept C2776607906 @default.
• W1939496645 hasConcept C2776715498 @default.
• W1939496645 hasConcept C2780206985 @default.
• W1939496645 hasConcept C501593827 @default.
• W1939496645 hasConcept C526171541 @default.
• W1939496645 hasConcept C55493867 @default.
• W1939496645 hasConcept C62231903 @default.
• W1939496645 hasConcept C71315377 @default.
• W1939496645 hasConcept C71924100 @default.
• W1939496645 hasConcept C87813604 @default.
• W1939496645 hasConcept C97320921 @default.
• W1939496645 hasConcept C98274493 @default.
• W1939496645 hasConceptScore W1939496645C109650736 @default.
• W1939496645 hasConceptScore W1939496645C112705442 @default.
• W1939496645 hasConceptScore W1939496645C126322002 @default.
• W1939496645 hasConceptScore W1939496645C134018914 @default.
• W1939496645 hasConceptScore W1939496645C142724271 @default.
• W1939496645 hasConceptScore W1939496645C185592680 @default.
• W1939496645 hasConceptScore W1939496645C204787440 @default.
• W1939496645 hasConceptScore W1939496645C27081682 @default.
• W1939496645 hasConceptScore W1939496645C2776607906 @default.
• W1939496645 hasConceptScore W1939496645C2776715498 @default.
• W1939496645 hasConceptScore W1939496645C2780206985 @default.
• W1939496645 hasConceptScore W1939496645C501593827 @default.
• W1939496645 hasConceptScore W1939496645C526171541 @default.
• W1939496645 hasConceptScore W1939496645C55493867 @default.
• W1939496645 hasConceptScore W1939496645C62231903 @default.
• W1939496645 hasConceptScore W1939496645C71315377 @default.
• W1939496645 hasConceptScore W1939496645C71924100 @default.
• W1939496645 hasConceptScore W1939496645C87813604 @default.

• next