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- W1939968253 abstract "There is increasing evidence that allium derivatives from garlic have significant antiproliferative actions on human cancers. Both hormone-responsive and hormone-unresponsive cells lines respond to these derivatives. The effects shown by allium derivatives include induction of apoptosis, regulation of cell cycle progression and modification of pathways of signal transduction. Allium derivatives appear to regulate nuclear factors involved in immune function and inflammation, as well as in cellular proliferation. Our own studies indicate that allium derivatives inhibit proliferation of the human prostate cancer cell line (LNCaP) and the human breast cancer cell line (MCF-7). Further research is required to clarify the mechanisms of inhibition of cellular proliferation by allium derivatives and to explore their potential application to cancer prevention and control." @default.
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- W1939968253 date "2001-03-01" @default.
- W1939968253 modified "2023-10-01" @default.
- W1939968253 title "Antiproliferative Effects of Allium Derivatives from Garlic" @default.
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- W1939968253 doi "https://doi.org/10.1093/jn/131.3.1058s" @default.
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