Matches in SemOpenAlex for { <https://semopenalex.org/work/W1940712340> ?p ?o ?g. }
Showing items 1 to 53 of
53
with 100 items per page.
- W1940712340 endingPage "200" @default.
- W1940712340 startingPage "191" @default.
- W1940712340 abstract "Reduced and cyanoethylated human ceruloplasmin form I was freed of sialic acid and digested by trypsin. A glycopeptide fraction isolated by gel filtration was separated into three carbohydrate-containing fractions by ion exchange chromatography on Dowex I. Each of these was further separated by column electrophoresis to yield a unique glycopeptide. With a stoichiometry of two chains per mole, these peptides account reasonably well for all the carbohydrate in the molecule. In a corresponding preparation from ceruloplasmin form II with smaller carbohydrate content, two of the glycopeptides were, present in greatly reduced amounts.The three glycopeptides were obtained in a pure state from sialic acid-containing ceruloplasmin form I by gel filtration, ion exchange chromatography, and column electrophoresis. Two different kinds of oligosaccharide chains were found attached to the purified peptides. The first contained 6 hexose, 5 glucosamine, 2 sialic acid, and 0.5 fucose residues; the other about 9 hexose, 8 glucosamine, 4 sialic acid, and 0.5 fucose residues. According to the composition of the protein, the larger chain accounts only for a small part of the carbohydrate content.On the basis of the results, it is proposed that human ceruloplasmin has six carbohydrate chains, three on each of two identical or nearly identical halves of the molecule. The carbohydrate chains are found in two different degrees of completion. Form II of the protein lacks 2–3 of these chains, having two particular sites partly unsubstituted." @default.
- W1940712340 created "2016-06-24" @default.
- W1940712340 creator A5082101100 @default.
- W1940712340 date "1971-01-01" @default.
- W1940712340 modified "2023-10-16" @default.
- W1940712340 title "Human ceruloplasmin as a polymorphic glycoprotein. Tryptic glycopeptides from two forms of the protein." @default.
- W1940712340 cites W1966481961 @default.
- W1940712340 cites W1997601409 @default.
- W1940712340 cites W2017470279 @default.
- W1940712340 cites W2025968522 @default.
- W1940712340 cites W2165671130 @default.
- W1940712340 cites W2916082882 @default.
- W1940712340 cites W4256645513 @default.
- W1940712340 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5126612" @default.
- W1940712340 hasPublicationYear "1971" @default.
- W1940712340 type Work @default.
- W1940712340 sameAs 1940712340 @default.
- W1940712340 citedByCount "4" @default.
- W1940712340 crossrefType "journal-article" @default.
- W1940712340 hasAuthorship W1940712340A5082101100 @default.
- W1940712340 hasConcept C108625454 @default.
- W1940712340 hasConcept C137610392 @default.
- W1940712340 hasConcept C185592680 @default.
- W1940712340 hasConcept C28452662 @default.
- W1940712340 hasConcept C501593827 @default.
- W1940712340 hasConcept C55493867 @default.
- W1940712340 hasConceptScore W1940712340C108625454 @default.
- W1940712340 hasConceptScore W1940712340C137610392 @default.
- W1940712340 hasConceptScore W1940712340C185592680 @default.
- W1940712340 hasConceptScore W1940712340C28452662 @default.
- W1940712340 hasConceptScore W1940712340C501593827 @default.
- W1940712340 hasConceptScore W1940712340C55493867 @default.
- W1940712340 hasIssue "4" @default.
- W1940712340 hasLocation W19407123401 @default.
- W1940712340 hasOpenAccess W1940712340 @default.
- W1940712340 hasPrimaryLocation W19407123401 @default.
- W1940712340 hasRelatedWork W1940712340 @default.
- W1940712340 hasRelatedWork W1981905369 @default.
- W1940712340 hasRelatedWork W1982892146 @default.
- W1940712340 hasRelatedWork W2005379190 @default.
- W1940712340 hasRelatedWork W201474726 @default.
- W1940712340 hasRelatedWork W2014788821 @default.
- W1940712340 hasRelatedWork W2057473302 @default.
- W1940712340 hasRelatedWork W2117398821 @default.
- W1940712340 hasRelatedWork W2605585491 @default.
- W1940712340 hasRelatedWork W2908272904 @default.
- W1940712340 hasVolume "3" @default.
- W1940712340 isParatext "false" @default.
- W1940712340 isRetracted "false" @default.
- W1940712340 magId "1940712340" @default.
- W1940712340 workType "article" @default.