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- W1941355959 abstract "Translation is the cellular process in which ribosomes make proteins from information encoded on messenger RNA (mRNA). We model translation with an exclusion process taking into account the experimentally determined, non-exponential, waiting time between steps of a ribosome. From numerical simulations using realistic parameter values, we determine the distribution P(E) of the number of proteins E produced by one mRNA. We find that for small E this distribution is not geometric. We present a simplified and analytically solvable semi-Markov model that relates P(E) to the distributions of the times to produce the first E proteins." @default.
- W1941355959 created "2016-06-24" @default.
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- W1941355959 date "2011-04-01" @default.
- W1941355959 modified "2023-09-27" @default.
- W1941355959 title "Semi-Markov models of mRNA-translation" @default.
- W1941355959 hasPublicationYear "2011" @default.
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