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- W194182275 abstract "Abstract : Peripheral nerve sheath tumors are the major tumors in neurofibromatosis type 1 (NF1). Malignant transformation of these tumors leads to extremely poor prognosis without therapy. The main goal of this project is to determine the efficacy of recombinant oncolytic herpes simplex type 1 viruses (HSV) for the therapy of nerve sheath tumors. To that aim we will generate reliable tumor models for malignant peripheral nerve sheath tumors (MPNST). Several existing oncolytic HSV will then be tested on these models for therapeutic utility. In addition, oncolytic therapy will be combined with experimental antiangiogenic therapy." @default.
- W194182275 created "2016-06-24" @default.
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- W194182275 date "2003-06-01" @default.
- W194182275 modified "2023-10-16" @default.
- W194182275 title "Therapy of Experimental Nerve Sheath Tumors Using Oncolytic Viruses" @default.
- W194182275 doi "https://doi.org/10.21236/ada417108" @default.
- W194182275 hasPublicationYear "2003" @default.
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