Matches in SemOpenAlex for { <https://semopenalex.org/work/W1942538422> ?p ?o ?g. }
- W1942538422 abstract "Insofar as recurrent spontaneous miscarriage (RSM) is linked with dysregulated immunity and inflammatory changes, and given the pro-inflammatory role of interleukin-21 (IL-21), we examined the association between IL-21 polymorphisms and RSM.IL-21 rs2055979, rs13143866, rs9992580, and rs4833837 were genotyped in 235 cases of RSM and 235 controls. Regression analysis was employed in assessing the contribution of IL-21 variants to the overall RSM risk. Higher minor allele and genotype frequencies of rs2055979 and rs13143866, but not rs9992580 or rs4833837, were seen in RSM patients than in the controls. IL-21 haplotype [rs9992580/rs4833837/rs2055979/rs13143866] analysis revealed a lower frequency of the TGCG haplotype, and a higher frequency of the GGCG and GAAA haplotypes in patients, thus conferring protection from or a susceptibility to RSM by these haplotypes respectively. Regression analysis confirmed the association of TGCG [OR (95%CI)=0.09 (0.05-0.16)], and GGCG [OR (95%CI)=2.52 (1.34-4.54)] and GAAA [OR (95%CI)=4.02 (2.20-7.70)] haplotypes, after adjusting for age and BMI.Our findings indicate that IL-21 is a novel susceptibility gene for RSM." @default.
- W1942538422 created "2016-06-24" @default.
- W1942538422 creator A5001288968 @default.
- W1942538422 creator A5013610398 @default.
- W1942538422 creator A5025310335 @default.
- W1942538422 creator A5045144382 @default.
- W1942538422 creator A5049528045 @default.
- W1942538422 creator A5051791762 @default.
- W1942538422 creator A5061993267 @default.
- W1942538422 creator A5087450329 @default.
- W1942538422 date "2011-06-01" @default.
- W1942538422 modified "2023-10-12" @default.
- W1942538422 title "Genetic variations in the interleukin-21 gene and the risk of recurrent idiopathic spontaneous miscarriage" @default.
- W1942538422 cites W1530426939 @default.
- W1942538422 cites W1557599456 @default.
- W1942538422 cites W1965354549 @default.
- W1942538422 cites W1969134054 @default.
- W1942538422 cites W1987867024 @default.
- W1942538422 cites W1988645670 @default.
- W1942538422 cites W2008713912 @default.
- W1942538422 cites W2010737442 @default.
- W1942538422 cites W2017332206 @default.
- W1942538422 cites W2032474425 @default.
- W1942538422 cites W2044063309 @default.
- W1942538422 cites W2053576831 @default.
- W1942538422 cites W2063568309 @default.
- W1942538422 cites W2079511996 @default.
- W1942538422 cites W2085894262 @default.
- W1942538422 cites W2112031080 @default.
- W1942538422 cites W2113198515 @default.
- W1942538422 cites W2124023185 @default.
- W1942538422 cites W2126520365 @default.
- W1942538422 cites W2153804701 @default.
- W1942538422 cites W2155013311 @default.
- W1942538422 cites W2161607224 @default.
- W1942538422 doi "https://doi.org/10.1684/ecn.2011.0287" @default.
- W1942538422 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21768062" @default.
- W1942538422 hasPublicationYear "2011" @default.
- W1942538422 type Work @default.
- W1942538422 sameAs 1942538422 @default.
- W1942538422 citedByCount "17" @default.
- W1942538422 countsByYear W19425384222012 @default.
- W1942538422 countsByYear W19425384222013 @default.
- W1942538422 countsByYear W19425384222014 @default.
- W1942538422 countsByYear W19425384222015 @default.
- W1942538422 countsByYear W19425384222016 @default.
- W1942538422 countsByYear W19425384222017 @default.
- W1942538422 countsByYear W19425384222019 @default.
- W1942538422 countsByYear W19425384222020 @default.
- W1942538422 countsByYear W19425384222021 @default.
- W1942538422 crossrefType "journal-article" @default.
- W1942538422 hasAuthorship W1942538422A5001288968 @default.
- W1942538422 hasAuthorship W1942538422A5013610398 @default.
- W1942538422 hasAuthorship W1942538422A5025310335 @default.
- W1942538422 hasAuthorship W1942538422A5045144382 @default.
- W1942538422 hasAuthorship W1942538422A5049528045 @default.
- W1942538422 hasAuthorship W1942538422A5051791762 @default.
- W1942538422 hasAuthorship W1942538422A5061993267 @default.
- W1942538422 hasAuthorship W1942538422A5087450329 @default.
- W1942538422 hasConcept C104317684 @default.
- W1942538422 hasConcept C126322002 @default.
- W1942538422 hasConcept C135763542 @default.
- W1942538422 hasConcept C180754005 @default.
- W1942538422 hasConcept C197754878 @default.
- W1942538422 hasConcept C203014093 @default.
- W1942538422 hasConcept C2778642596 @default.
- W1942538422 hasConcept C2778690821 @default.
- W1942538422 hasConcept C2779234561 @default.
- W1942538422 hasConcept C2780625311 @default.
- W1942538422 hasConcept C54355233 @default.
- W1942538422 hasConcept C71924100 @default.
- W1942538422 hasConcept C74172505 @default.
- W1942538422 hasConcept C86803240 @default.
- W1942538422 hasConceptScore W1942538422C104317684 @default.
- W1942538422 hasConceptScore W1942538422C126322002 @default.
- W1942538422 hasConceptScore W1942538422C135763542 @default.
- W1942538422 hasConceptScore W1942538422C180754005 @default.
- W1942538422 hasConceptScore W1942538422C197754878 @default.
- W1942538422 hasConceptScore W1942538422C203014093 @default.
- W1942538422 hasConceptScore W1942538422C2778642596 @default.
- W1942538422 hasConceptScore W1942538422C2778690821 @default.
- W1942538422 hasConceptScore W1942538422C2779234561 @default.
- W1942538422 hasConceptScore W1942538422C2780625311 @default.
- W1942538422 hasConceptScore W1942538422C54355233 @default.
- W1942538422 hasConceptScore W1942538422C71924100 @default.
- W1942538422 hasConceptScore W1942538422C74172505 @default.
- W1942538422 hasConceptScore W1942538422C86803240 @default.
- W1942538422 hasLocation W19425384221 @default.
- W1942538422 hasLocation W19425384222 @default.
- W1942538422 hasOpenAccess W1942538422 @default.
- W1942538422 hasPrimaryLocation W19425384221 @default.
- W1942538422 hasRelatedWork W1535544375 @default.
- W1942538422 hasRelatedWork W1970313935 @default.
- W1942538422 hasRelatedWork W1972613299 @default.
- W1942538422 hasRelatedWork W1974748046 @default.
- W1942538422 hasRelatedWork W2010740953 @default.
- W1942538422 hasRelatedWork W2022146009 @default.
- W1942538422 hasRelatedWork W2059127341 @default.
- W1942538422 hasRelatedWork W2063816017 @default.
- W1942538422 hasRelatedWork W2081104043 @default.