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- W194295354 abstract "No AccessJournal of Urology1 Sep 1987Vasoactive Intracavernous Pharmacotherapy for the Treatment of Erectile Impotence in Men with Spinal Cord Injury Abraham Ami Sidi, Jeffrey S. Cameron, Dennis D. Dykstra, Yuri Reinberg, and Paul H. Lange Abraham Ami SidiAbraham Ami Sidi More articles by this author , Jeffrey S. CameronJeffrey S. Cameron More articles by this author , Dennis D. DykstraDennis D. Dykstra More articles by this author , Yuri ReinbergYuri Reinberg More articles by this author , and Paul H. LangePaul H. Lange More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)43252-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail A total of 66 spinal cord injury patients with erectile dysfunction entered a protocol of penile intracavernous pharmacotherapy with papaverine hydrochloride (30mg. per ml.) or a combination of papaverine (25mg. per ml.) and phentolamine mesylate (0.83mg. per ml.) in an attempt to restore erectile function. Of the patients 52 completed the protocol and all achieved transient functional penile erections after administration of the drug. Of the 52 responders 71 per cent currently practice self-injection as a method to restore erectile function. Sustained erections that required irrigation of the cavernous bodies with alpha-adrenergic agents developed in 4 patients and 1 suffered localized intracorporeal induration. If the long-term followup shows that complications remain relatively minor, undoubtedly vasoactive intracavernous pharmacotherapy will have a major role in the restoration of erectile function in the motivated man with spinal cord injury. However, in view of the unknown long-term effects and potential dangers of this approach it is important that patients adhere to a strict drug injection protocol under the supervision of qualified urologists who are familiar with the potential risks and complications. (J. Urol., 138: 539–542, 1987) © 1987 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byBechara A, Casabe A, Cheliz G, Romano S, Rey H and Fredotovich N (2018) Comparative Study of Papaverine Plus Phentolamine Versus Prostaglandin E1 in Erectile DysfunctionJournal of Urology, VOL. 157, NO. 6, (2132-2134), Online publication date: 1-Jun-1997.Bemelmans B, Meuleman E, Anten B, Doesburg W, Van Kerrebroeck P and Debruyne F (2018) Penile Sensory Disorders in Erectile Dysfunction: Results of a Comprehensive Neuro-Urophysiological Diagnostic Evaluation in 123 PatientsJournal of Urology, VOL. 146, NO. 3, (777-782), Online publication date: 1-Sep-1991.Sidi A, Reddy P and Chen K (2018) Patient Acceptance of and Satisfaction with Vasoactive Intracavernous Pharmacotherapy for ImpotenceJournal of Urology, VOL. 140, NO. 2, (293-294), Online publication date: 1-Aug-1988.Collins K and Hackler R (2018) Complications of Penile Prostheses in the Spinal Cord Injury PopulationJournal of Urology, VOL. 140, NO. 5 Part 1, (984-985), Online publication date: 1-Nov-1988.Duffy L, Sidi A and Lange P (2018) Vasoactive Intracavernous Pharmacotherapy—The Nursing Role in Teaching Self-Injection TherapyJournal of Urology, VOL. 138, NO. 5, (1198-1200), Online publication date: 1-Nov-1987. Volume 138Issue 3September 1987Page: 539-542 Advertisement Copyright & Permissions© 1987 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Abraham Ami Sidi More articles by this author Jeffrey S. Cameron More articles by this author Dennis D. Dykstra More articles by this author Yuri Reinberg More articles by this author Paul H. Lange More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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- W194295354 title "Vasoactive Intracavernous Pharmacotherapy for the Treatment of Erectile Impotence in Men with Spinal Cord Injury" @default.
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