Matches in SemOpenAlex for { <https://semopenalex.org/work/W194317801> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W194317801 endingPage "309" @default.
- W194317801 startingPage "295" @default.
- W194317801 abstract "A complete knowledge of mitochondrial gene expression demands an understanding of the events involved in the initiation, elongation, termination, and maturation of mitochondrial transcripts. Whereas many significant features of the processing of the 21S and 14S rRNAs and the cob and oxi3 transcripts have been elucidated (Church et al. 1979; Bonitz et al. 1980; Bos et al. 1980; Halbreich et al. 1980; Merten et al. 1980; Van Ommen et al. 1980), virtually nothing is known about the regulation of the synthesis of the primary transcripts for these genes. In this paper we present some of our results concerning the localization of the sites for the initiation of RNA synthesis in the mitochondrial genome. We have found multiple initiation sites in the yeast mitochondrial genome, in contrast to the situation observed in mammalian mitochondria. In addition, we describe our studies concerning the role of the mtRNA polymerase in the regulation of mitochondrial biogenesis. Because of the extensive processing of mitochondrial transcripts and the lack of promoter mutations, the sites for the initiation of mtRNA synthesis have not been identified by conventional biochemical and genetic methods. Assuming that mitochondrial transcripts are initiated with a 5′-triphosphate nucleotide, and since there is no evidence for in vivo capping of mitochondrial transcripts, we have exploited the properties of the vaccinia virus guanylyltransferase to label transcripts retaining their original 5′ ends. This enzyme catalyzes the coupling of GTP to a polyribonucleotide terminated with a diphosphate or triphosphate (Martin and Moss 1975; Martin et al. 1975; Monroy..." @default.
- W194317801 created "2016-06-24" @default.
- W194317801 creator A5003330445 @default.
- W194317801 creator A5011898982 @default.
- W194317801 creator A5012132645 @default.
- W194317801 creator A5013359694 @default.
- W194317801 creator A5040178560 @default.
- W194317801 creator A5049026703 @default.
- W194317801 creator A5060703074 @default.
- W194317801 date "1982-01-01" @default.
- W194317801 modified "2023-09-24" @default.
- W194317801 title "Transcriptional Initiation of Yeast Mitochondrial RNA and Characterization and Synthesis of Mitochondrial RNA Polymerase" @default.
- W194317801 doi "https://doi.org/10.1101/087969145.12.295" @default.
- W194317801 hasPublicationYear "1982" @default.
- W194317801 type Work @default.
- W194317801 sameAs 194317801 @default.
- W194317801 citedByCount "0" @default.
- W194317801 crossrefType "journal-article" @default.
- W194317801 hasAuthorship W194317801A5003330445 @default.
- W194317801 hasAuthorship W194317801A5011898982 @default.
- W194317801 hasAuthorship W194317801A5012132645 @default.
- W194317801 hasAuthorship W194317801A5013359694 @default.
- W194317801 hasAuthorship W194317801A5040178560 @default.
- W194317801 hasAuthorship W194317801A5049026703 @default.
- W194317801 hasAuthorship W194317801A5060703074 @default.
- W194317801 hasConcept C101762097 @default.
- W194317801 hasConcept C102568066 @default.
- W194317801 hasConcept C104317684 @default.
- W194317801 hasConcept C150194340 @default.
- W194317801 hasConcept C153911025 @default.
- W194317801 hasConcept C24586158 @default.
- W194317801 hasConcept C2776449523 @default.
- W194317801 hasConcept C2777229759 @default.
- W194317801 hasConcept C28859421 @default.
- W194317801 hasConcept C54355233 @default.
- W194317801 hasConcept C64350747 @default.
- W194317801 hasConcept C67705224 @default.
- W194317801 hasConcept C82381507 @default.
- W194317801 hasConcept C86803240 @default.
- W194317801 hasConceptScore W194317801C101762097 @default.
- W194317801 hasConceptScore W194317801C102568066 @default.
- W194317801 hasConceptScore W194317801C104317684 @default.
- W194317801 hasConceptScore W194317801C150194340 @default.
- W194317801 hasConceptScore W194317801C153911025 @default.
- W194317801 hasConceptScore W194317801C24586158 @default.
- W194317801 hasConceptScore W194317801C2776449523 @default.
- W194317801 hasConceptScore W194317801C2777229759 @default.
- W194317801 hasConceptScore W194317801C28859421 @default.
- W194317801 hasConceptScore W194317801C54355233 @default.
- W194317801 hasConceptScore W194317801C64350747 @default.
- W194317801 hasConceptScore W194317801C67705224 @default.
- W194317801 hasConceptScore W194317801C82381507 @default.
- W194317801 hasConceptScore W194317801C86803240 @default.
- W194317801 hasLocation W1943178011 @default.
- W194317801 hasOpenAccess W194317801 @default.
- W194317801 hasPrimaryLocation W1943178011 @default.
- W194317801 hasRelatedWork W130125611 @default.
- W194317801 hasRelatedWork W1773955914 @default.
- W194317801 hasRelatedWork W181386649 @default.
- W194317801 hasRelatedWork W1907337082 @default.
- W194317801 hasRelatedWork W1978001298 @default.
- W194317801 hasRelatedWork W2004801766 @default.
- W194317801 hasRelatedWork W2034128994 @default.
- W194317801 hasRelatedWork W2054677550 @default.
- W194317801 hasRelatedWork W2056695210 @default.
- W194317801 hasRelatedWork W2083355097 @default.
- W194317801 hasRelatedWork W2088001012 @default.
- W194317801 hasRelatedWork W2103221638 @default.
- W194317801 hasRelatedWork W2136861527 @default.
- W194317801 hasRelatedWork W2811330735 @default.
- W194317801 hasRelatedWork W2968948476 @default.
- W194317801 hasRelatedWork W2982429991 @default.
- W194317801 hasRelatedWork W47812609 @default.
- W194317801 hasRelatedWork W63993687 @default.
- W194317801 hasRelatedWork W977137979 @default.
- W194317801 hasRelatedWork W2181992954 @default.
- W194317801 hasVolume "12" @default.
- W194317801 isParatext "false" @default.
- W194317801 isRetracted "false" @default.
- W194317801 magId "194317801" @default.
- W194317801 workType "article" @default.