FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1943341485> ?p ?o ?g. }

• W1943341485 endingPage "1489" @default.
• W1943341485 startingPage "1483" @default.
• W1943341485 abstract "Autofluorescence bronchoscopy (AFB) and computed tomography (CT) enable lung cancer (LC) detection at the early (pre-)invasive stage. However, LC risk in patients with preinvasive endobronchial lesions is unclear.To assess LC incidence and identify potential risk determinants in patients with preinvasive lesions.In our tertiary care referral center, 164 subjects with preinvasive lesions were monitored up to 12.5 years by repeated AFB and CT. Occurrence of LC was monitored. Clinical management depended on histological grade, with cancer patients receiving standard care. Potential risk determinants (smoking status, baseline histology, cancer history, and chronic obstructive pulmonary disease [COPD] status) were evaluated in relation to cancer occurrence, event-free survival (EFS), and overall survival (OS).During surveillance (median of 30 mo, range 4-152) of 164 subjects with preinvasive lesions (80 high grade and 84 low grade at inclusion), 61 LCs were detected in 55 subjects (median time to event 16.5 mo). Twenty-three LCs (38%) were detected by CT, and 38 (62%) were detected by AFB. More cancers (36 of 61; 59%) developed from separate, rather than initial lesional sites. Subjects with high-grade lesions were more likely to be diagnosed with LC at the same or another site in the lungs than those with low-grade lesions (P = 0.03). Independent risk determinants for OS were previous curatively treated cancer and COPD (P ≤ 0.05).Presence of preinvasive lesions, especially high-grade lesions, may serve as LC risk markers. LCs occur both at preinvasive lesion sites and elsewhere in the bronchial epithelium or lung parenchyma. Prospective validation of biomarkers and randomized intervention studies are needed to determine optimal management strategies." @default.
• W1943341485 created "2016-06-24" @default.
• W1943341485 creator A5016904876 @default.
• W1943341485 creator A5018150637 @default.
• W1943341485 creator A5029129546 @default.
• W1943341485 creator A5049451329 @default.
• W1943341485 creator A5050340051 @default.
• W1943341485 creator A5051650713 @default.
• W1943341485 creator A5054688262 @default.
• W1943341485 creator A5057813082 @default.
• W1943341485 creator A5058046256 @default.
• W1943341485 creator A5075942051 @default.
• W1943341485 creator A5084123868 @default.
• W1943341485 creator A5089161005 @default.
• W1943341485 date "2015-12-15" @default.
• W1943341485 modified "2023-10-17" @default.
• W1943341485 title "Close Surveillance with Long-Term Follow-up of Subjects with Preinvasive Endobronchial Lesions" @default.
• W1943341485 cites W1158033259 @default.
• W1943341485 cites W130099911 @default.
• W1943341485 cites W1505708219 @default.
• W1943341485 cites W1874994109 @default.
• W1943341485 cites W1964240785 @default.
• W1943341485 cites W1967718615 @default.
• W1943341485 cites W1973315596 @default.
• W1943341485 cites W1975361135 @default.
• W1943341485 cites W1981989535 @default.
• W1943341485 cites W1988662657 @default.
• W1943341485 cites W2052789795 @default.
• W1943341485 cites W2054951030 @default.
• W1943341485 cites W2058052840 @default.
• W1943341485 cites W2065906711 @default.
• W1943341485 cites W2084115652 @default.
• W1943341485 cites W2084829978 @default.
• W1943341485 cites W2091283166 @default.
• W1943341485 cites W2101995865 @default.
• W1943341485 cites W2107668508 @default.
• W1943341485 cites W2112971584 @default.
• W1943341485 cites W2115585647 @default.
• W1943341485 cites W2125247967 @default.
• W1943341485 cites W2125514375 @default.
• W1943341485 cites W2137086955 @default.
• W1943341485 cites W2138960985 @default.
• W1943341485 cites W2140664514 @default.
• W1943341485 cites W2141467076 @default.
• W1943341485 cites W2146532280 @default.
• W1943341485 cites W2154308385 @default.
• W1943341485 cites W2158458810 @default.
• W1943341485 cites W2161698422 @default.
• W1943341485 doi "https://doi.org/10.1164/rccm.201504-0822oc" @default.
• W1943341485 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26275031" @default.
• W1943341485 hasPublicationYear "2015" @default.
• W1943341485 type Work @default.
• W1943341485 sameAs 1943341485 @default.
• W1943341485 citedByCount "34" @default.
• W1943341485 countsByYear W19433414852015 @default.
• W1943341485 countsByYear W19433414852016 @default.
• W1943341485 countsByYear W19433414852017 @default.
• W1943341485 countsByYear W19433414852018 @default.
• W1943341485 countsByYear W19433414852019 @default.
• W1943341485 countsByYear W19433414852020 @default.
• W1943341485 countsByYear W19433414852021 @default.
• W1943341485 countsByYear W19433414852022 @default.
• W1943341485 countsByYear W19433414852023 @default.
• W1943341485 crossrefType "journal-article" @default.
• W1943341485 hasAuthorship W1943341485A5016904876 @default.
• W1943341485 hasAuthorship W1943341485A5018150637 @default.
• W1943341485 hasAuthorship W1943341485A5029129546 @default.
• W1943341485 hasAuthorship W1943341485A5049451329 @default.
• W1943341485 hasAuthorship W1943341485A5050340051 @default.
• W1943341485 hasAuthorship W1943341485A5051650713 @default.
• W1943341485 hasAuthorship W1943341485A5054688262 @default.
• W1943341485 hasAuthorship W1943341485A5057813082 @default.
• W1943341485 hasAuthorship W1943341485A5058046256 @default.
• W1943341485 hasAuthorship W1943341485A5075942051 @default.
• W1943341485 hasAuthorship W1943341485A5084123868 @default.
• W1943341485 hasAuthorship W1943341485A5089161005 @default.
• W1943341485 hasBestOaLocation W19433414852 @default.
• W1943341485 hasConcept C121608353 @default.
• W1943341485 hasConcept C126322002 @default.
• W1943341485 hasConcept C126838900 @default.
• W1943341485 hasConcept C142724271 @default.
• W1943341485 hasConcept C146357865 @default.
• W1943341485 hasConcept C151730666 @default.
• W1943341485 hasConcept C2776256026 @default.
• W1943341485 hasConcept C2776780178 @default.
• W1943341485 hasConcept C2777714996 @default.
• W1943341485 hasConcept C2778996910 @default.
• W1943341485 hasConcept C2781156865 @default.
• W1943341485 hasConcept C57742111 @default.
• W1943341485 hasConcept C71924100 @default.
• W1943341485 hasConcept C86803240 @default.
• W1943341485 hasConcept C90924648 @default.
• W1943341485 hasConceptScore W1943341485C121608353 @default.
• W1943341485 hasConceptScore W1943341485C126322002 @default.
• W1943341485 hasConceptScore W1943341485C126838900 @default.
• W1943341485 hasConceptScore W1943341485C142724271 @default.
• W1943341485 hasConceptScore W1943341485C146357865 @default.
• W1943341485 hasConceptScore W1943341485C151730666 @default.

• next