Matches in SemOpenAlex for { <https://semopenalex.org/work/W1945081595> ?p ?o ?g. }
- W1945081595 endingPage "43" @default.
- W1945081595 startingPage "29" @default.
- W1945081595 abstract "Abstract Mutations in the Start class of cell division cycle genes (CDC28, CDC36 and CDC39) define the point in the G1 phase of the vegetative cycle at which the cell becomes committed to completing another round of cell division. Genetic, cytological and biochemical data demonstrate that these mutations cause meiotic cells to become arrested at pachytene following completion of both chromosomal DNA replication and spindle pole body (SPB) duplication. In contrast these mutations have previously been found to cause arrest of the mitotic cell cycle prior to either of these landmark events, so the role of the Start genes in these events during vegetative growth must be indirect. Our observations are consistent with the hypothesis that CDC28, CDC36 and CDC39 are required for irreversible commitment to nuclear division in both the mitotic and meiotic pathways. CDC28 was additionally found to be required for the SPB separation that precedes spindle formation in preparation for the second meiotic division. Cytological and genetic analyses of this requirement revealed both that such separation may fail independently at either SPB and that ascospore formation can proceed independently of SPB separation." @default.
- W1945081595 created "2016-06-24" @default.
- W1945081595 creator A5012812883 @default.
- W1945081595 creator A5018082085 @default.
- W1945081595 date "1989-09-01" @default.
- W1945081595 modified "2023-10-10" @default.
- W1945081595 title "Pachytene arrest and other meiotic effects of the start mutations in Saccharomyces cerevisiae." @default.
- W1945081595 cites W124437672 @default.
- W1945081595 cites W1559822611 @default.
- W1945081595 cites W1613199479 @default.
- W1945081595 cites W1632562505 @default.
- W1945081595 cites W1635646186 @default.
- W1945081595 cites W1749612483 @default.
- W1945081595 cites W1781715134 @default.
- W1945081595 cites W1894157107 @default.
- W1945081595 cites W1936822081 @default.
- W1945081595 cites W1966797426 @default.
- W1945081595 cites W1966838307 @default.
- W1945081595 cites W1968393883 @default.
- W1945081595 cites W1987350343 @default.
- W1945081595 cites W1993882349 @default.
- W1945081595 cites W1994736093 @default.
- W1945081595 cites W2011131394 @default.
- W1945081595 cites W2018215453 @default.
- W1945081595 cites W2022752383 @default.
- W1945081595 cites W2032196263 @default.
- W1945081595 cites W2032545491 @default.
- W1945081595 cites W2035101804 @default.
- W1945081595 cites W2054649439 @default.
- W1945081595 cites W2054863303 @default.
- W1945081595 cites W2059695028 @default.
- W1945081595 cites W2063630475 @default.
- W1945081595 cites W2070388092 @default.
- W1945081595 cites W2078906089 @default.
- W1945081595 cites W2082553124 @default.
- W1945081595 cites W2087621755 @default.
- W1945081595 cites W2089304281 @default.
- W1945081595 cites W2101769299 @default.
- W1945081595 cites W2102242413 @default.
- W1945081595 cites W2103539424 @default.
- W1945081595 cites W2105924300 @default.
- W1945081595 cites W2116063228 @default.
- W1945081595 cites W2117939247 @default.
- W1945081595 cites W2125992715 @default.
- W1945081595 cites W2130114875 @default.
- W1945081595 cites W2134490854 @default.
- W1945081595 cites W2136101954 @default.
- W1945081595 cites W2139747672 @default.
- W1945081595 cites W2155507858 @default.
- W1945081595 cites W2156160417 @default.
- W1945081595 cites W2157083171 @default.
- W1945081595 cites W2160824627 @default.
- W1945081595 cites W2182728969 @default.
- W1945081595 cites W2183518601 @default.
- W1945081595 cites W2187095353 @default.
- W1945081595 cites W2231143971 @default.
- W1945081595 cites W2423103033 @default.
- W1945081595 cites W991504569 @default.
- W1945081595 cites W130722359 @default.
- W1945081595 doi "https://doi.org/10.1093/genetics/123.1.29" @default.
- W1945081595 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1203788" @default.
- W1945081595 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2680756" @default.
- W1945081595 hasPublicationYear "1989" @default.
- W1945081595 type Work @default.
- W1945081595 sameAs 1945081595 @default.
- W1945081595 citedByCount "133" @default.
- W1945081595 countsByYear W19450815952012 @default.
- W1945081595 countsByYear W19450815952013 @default.
- W1945081595 countsByYear W19450815952014 @default.
- W1945081595 countsByYear W19450815952015 @default.
- W1945081595 countsByYear W19450815952016 @default.
- W1945081595 countsByYear W19450815952017 @default.
- W1945081595 countsByYear W19450815952018 @default.
- W1945081595 countsByYear W19450815952019 @default.
- W1945081595 countsByYear W19450815952023 @default.
- W1945081595 crossrefType "journal-article" @default.
- W1945081595 hasAuthorship W1945081595A5012812883 @default.
- W1945081595 hasAuthorship W1945081595A5018082085 @default.
- W1945081595 hasBestOaLocation W19450815951 @default.
- W1945081595 hasConcept C104317684 @default.
- W1945081595 hasConcept C120504264 @default.
- W1945081595 hasConcept C148196450 @default.
- W1945081595 hasConcept C1491633281 @default.
- W1945081595 hasConcept C2777576037 @default.
- W1945081595 hasConcept C29537977 @default.
- W1945081595 hasConcept C47432576 @default.
- W1945081595 hasConcept C501734568 @default.
- W1945081595 hasConcept C54355233 @default.
- W1945081595 hasConcept C70547292 @default.
- W1945081595 hasConcept C7602840 @default.
- W1945081595 hasConcept C85813293 @default.
- W1945081595 hasConcept C86803240 @default.
- W1945081595 hasConcept C93304396 @default.
- W1945081595 hasConcept C95444343 @default.
- W1945081595 hasConceptScore W1945081595C104317684 @default.
- W1945081595 hasConceptScore W1945081595C120504264 @default.
- W1945081595 hasConceptScore W1945081595C148196450 @default.
- W1945081595 hasConceptScore W1945081595C1491633281 @default.