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- W1946011282 abstract "Due to the emergence of multi-drug resistant Mycobacterium tuberculosis strains, there is an urgent need to search for new antimycobacterial drugs. The present work describes the bioactivity-guided fractionation of Chamaedora tepejilote hexane extract which led to the isolation and the characterization of squalene, farnesol, methylic ester of hexadecanoic acid, β-sitosterol and ursolic acid. Activity against Mycobacterium tuberculosis H37Rv, determined by radiorespirometric Bactec assay, showed ursolic acid, squalene and farnesol to produce a M. tuberculosis growth inhibition of 99% at a concentration of 100 µg/mL. Copyright © 2005 John Wiley & Sons, Ltd." @default.
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- W1946011282 date "2005-01-01" @default.
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- W1946011282 title "Secondary Metabolites fromChamaedora tepejilote (Palmae) are Active againstMycobacterium tuberculosis" @default.
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- W1946011282 doi "https://doi.org/10.1002/ptr.1664" @default.
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