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• W1946094993 abstract "The intracellular fate of Chlamydia psittaci during infection of a monocytic cell line, THP1, was characterized. Cytochalasin D inhibited phagocytosis of latex beads but had no effect on infection by C. psittaci, and vacuoles expressed the transferrin receptor, suggesting accessibility to the endocytic pathway. Early Chlamydia-containing vacuoles expressed major histocompatibility complex (MHC) class I molecules, and most vacuoles fused with host cell lysosomes, since they expressed LAMP-1 and had acidic pHs. In cells prestimulated with gamma interferon, vacuoles also expressed MHC class II molecules, suggesting that the monocytes might effectively process Chlamydia-derived antigens for presentation by MHC class I and class II molecules." @default.
• W1946094993 created "2016-06-24" @default.
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• W1946094993 date "1997-06-01" @default.
• W1946094993 modified "2023-10-03" @default.
• W1946094993 title "Distribution of endosomal, lysosomal, and major histocompatability complex markers in a monocytic cell line infected with Chlamydia psittaci" @default.
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• W1946094993 doi "https://doi.org/10.1128/iai.65.6.2437-2442.1997" @default.
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