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• W1946155622 abstract "We compared infection of a murine macrophage-like cell line, J774-1, with two Theiler's murine encephalomyelitis virus subgroup strains. The GDVII strain, which is highly virulent and produces acute polioencephalomyelitis in mice, did not actively replicate in J774-1 cells, although there was a significant inhibition in cellular protein synthesis. In contrast, the DA strain, which is less virulent and causes demyelination with a persistent virus infection, productively infected J774-1 cells; however, there was less virus produced than in BHK-21 cells, and there was little if any cellular protein shutoff. These in vitro data may provide some explanation for the biological activities that are observed between both subgroup strains." @default.
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• W1946155622 date "1997-01-01" @default.
• W1946155622 modified "2023-10-16" @default.
• W1946155622 title "Theiler's murine encephalomyelitis virus subgroup strain-specific infection in a murine macrophage-like cell line" @default.
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• W1946155622 doi "https://doi.org/10.1128/jvi.71.1.729-733.1997" @default.
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