FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1946352954> ?p ?o ?g. }

• W1946352954 endingPage "2037" @default.
• W1946352954 startingPage "2032" @default.
• W1946352954 abstract "Abstract Background Intraductal papillary mucinous neoplasm ( IPMN ) is a well‐established entity among pancreatic neoplasms that ranges from low‐grade dysplasia to invasive carcinoma. Epithelial‐mesenchymal transition ( EMT ) contributes to tumor progression in various cancers. Moreover, N otch signaling is one of the important upstream effectors of EMT promotion. Currently, it is unclear whether EMT causes pathological progression of IPMN . Aim We evaluated the expression of EMT ‐promoting transcription factors T wist and B cell‐specific M oloney murine leukemia virus insertion site 1 ( B mi1) in IPMN . Methods Patients who underwent resections at our institute and its affiliated hospital were enrolled in this study ( n = 35). Protein expression of EMT markers T wist, B mi1, J agged1, and E ‐cadherin in resected specimens was investigated by immunohistochemistry. Expression of these proteins was compared with the clinicopathological factors and patient survival. Results Positive expression of T wist and B mi1 was observed in 40.0% and 42.9% of IPMNs , respectively. T wist and B mi1 expression was significantly higher in IPMN s with high‐grade dysplasia ( P < 0.05) and invasive carcinoma ( P < 0.05) than that in IPMN s with low‐grade dysplasia. High expression of T wist was correlated with J agged1 expression and inversely correlated with expression of E ‐cadherin ( P = 0.06 and P < 0.05, respectively). In survival analyses, the recurrence rate was significantly higher in the group that showed simultaneous high expression of T wist and B mi1 ( P < 0.05). Conclusions Expression of T wist and B mi1 is associated with aggressiveness and poor prognoses of IPMN through EMT promotion that might be induced by N otch signaling." @default.
• W1946352954 created "2016-06-24" @default.
• W1946352954 creator A5004189291 @default.
• W1946352954 creator A5010934625 @default.
• W1946352954 creator A5013914944 @default.
• W1946352954 creator A5015300248 @default.
• W1946352954 creator A5030227876 @default.
• W1946352954 creator A5039080422 @default.
• W1946352954 creator A5042299336 @default.
• W1946352954 creator A5048946839 @default.
• W1946352954 creator A5051832340 @default.
• W1946352954 creator A5055604473 @default.
• W1946352954 creator A5066565101 @default.
• W1946352954 date "2014-11-18" @default.
• W1946352954 modified "2023-10-06" @default.
• W1946352954 title "Effect of Twist and Bmi1 on intraductal papillary mucinous neoplasm of the pancreas" @default.
• W1946352954 cites W1711861384 @default.
• W1946352954 cites W1964081206 @default.
• W1946352954 cites W1973541913 @default.
• W1946352954 cites W1977289089 @default.
• W1946352954 cites W1977962361 @default.
• W1946352954 cites W2013054658 @default.
• W1946352954 cites W2022557585 @default.
• W1946352954 cites W2027719459 @default.
• W1946352954 cites W2029572381 @default.
• W1946352954 cites W2036008499 @default.
• W1946352954 cites W2039298921 @default.
• W1946352954 cites W2042087070 @default.
• W1946352954 cites W2042198997 @default.
• W1946352954 cites W2047992261 @default.
• W1946352954 cites W2050386266 @default.
• W1946352954 cites W2059519664 @default.
• W1946352954 cites W2061662334 @default.
• W1946352954 cites W2062759109 @default.
• W1946352954 cites W2066796744 @default.
• W1946352954 cites W2071696803 @default.
• W1946352954 cites W2076375511 @default.
• W1946352954 cites W2079016331 @default.
• W1946352954 cites W2080870201 @default.
• W1946352954 cites W2083798214 @default.
• W1946352954 cites W2086548243 @default.
• W1946352954 cites W2091154399 @default.
• W1946352954 cites W2097598334 @default.
• W1946352954 cites W2106548070 @default.
• W1946352954 cites W2132695443 @default.
• W1946352954 cites W2135739626 @default.
• W1946352954 cites W2148000660 @default.
• W1946352954 cites W2148560417 @default.
• W1946352954 cites W2151163394 @default.
• W1946352954 cites W2151598146 @default.
• W1946352954 cites W2167808312 @default.
• W1946352954 cites W2169482850 @default.
• W1946352954 cites W2170086508 @default.
• W1946352954 cites W2325799897 @default.
• W1946352954 cites W4233166454 @default.
• W1946352954 doi "https://doi.org/10.1111/jgh.12652" @default.
• W1946352954 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24909638" @default.
• W1946352954 hasPublicationYear "2014" @default.
• W1946352954 type Work @default.
• W1946352954 sameAs 1946352954 @default.
• W1946352954 citedByCount "15" @default.
• W1946352954 countsByYear W19463529542012 @default.
• W1946352954 countsByYear W19463529542015 @default.
• W1946352954 countsByYear W19463529542016 @default.
• W1946352954 countsByYear W19463529542017 @default.
• W1946352954 countsByYear W19463529542020 @default.
• W1946352954 countsByYear W19463529542021 @default.
• W1946352954 countsByYear W19463529542022 @default.
• W1946352954 countsByYear W19463529542023 @default.
• W1946352954 crossrefType "journal-article" @default.
• W1946352954 hasAuthorship W1946352954A5004189291 @default.
• W1946352954 hasAuthorship W1946352954A5010934625 @default.
• W1946352954 hasAuthorship W1946352954A5013914944 @default.
• W1946352954 hasAuthorship W1946352954A5015300248 @default.
• W1946352954 hasAuthorship W1946352954A5030227876 @default.
• W1946352954 hasAuthorship W1946352954A5039080422 @default.
• W1946352954 hasAuthorship W1946352954A5042299336 @default.
• W1946352954 hasAuthorship W1946352954A5048946839 @default.
• W1946352954 hasAuthorship W1946352954A5051832340 @default.
• W1946352954 hasAuthorship W1946352954A5055604473 @default.
• W1946352954 hasAuthorship W1946352954A5066565101 @default.
• W1946352954 hasConcept C126322002 @default.
• W1946352954 hasConcept C142724271 @default.
• W1946352954 hasConcept C143998085 @default.
• W1946352954 hasConcept C204232928 @default.
• W1946352954 hasConcept C2775894508 @default.
• W1946352954 hasConcept C2776469228 @default.
• W1946352954 hasConcept C2778764654 @default.
• W1946352954 hasConcept C71924100 @default.
• W1946352954 hasConcept C90924648 @default.
• W1946352954 hasConceptScore W1946352954C126322002 @default.
• W1946352954 hasConceptScore W1946352954C142724271 @default.
• W1946352954 hasConceptScore W1946352954C143998085 @default.
• W1946352954 hasConceptScore W1946352954C204232928 @default.
• W1946352954 hasConceptScore W1946352954C2775894508 @default.
• W1946352954 hasConceptScore W1946352954C2776469228 @default.
• W1946352954 hasConceptScore W1946352954C2778764654 @default.
• W1946352954 hasConceptScore W1946352954C71924100 @default.

• next