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- W1946372128 abstract "Karyotypes of two transplantable murine ascites leukemias, LBN/a2 and LBN/b3, were studied with the use of the trypsIn-Giemsa technique. The original tumors arose in adult female mice of strains BN/a and BN/b after prolonged antilymphocyte globulin administration. The karyotypes of both leukemias showed similar patterns. Both were hyperdiploid with modal chromosome numbers of 41 and 42 in LBN/a2 and LBN/b3, respectively. The cells consisted of an average of 37 normal chromosomes and 4–5 abnormal chromosomes. The most consistent karyotype deviation was monosomy of the X-chromosome and of several autosomes: #9, 14, and 7 in the LBN/a2 line and #7, 12, 14, and 9 In the LBN/b3 line. in most LBN/b3 cells and in a lower proportion of LBN/a2 cells, trisomy of chromosome #15 was found. With regard to the occurrence of abnormal marker chromosomes, both tumors exhibited great cell-to-cell variation. Two of the markers were common to both leukemia lines." @default.
- W1946372128 created "2016-06-24" @default.
- W1946372128 date "1979-04-01" @default.
- W1946372128 modified "2023-10-17" @default.
- W1946372128 title "Chromosome Studies of Two Transplantable Leukemias of BN Mice<xref ref-type=fn rid=FN2>2</xref>" @default.
- W1946372128 doi "https://doi.org/10.1093/jnci/62.4.1051" @default.
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- W1946372128 hasPublicationYear "1979" @default.
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