FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1946571802> ?p ?o ?g. }

• W1946571802 endingPage "851" @default.
• W1946571802 startingPage "842" @default.
• W1946571802 abstract "To evaluate the possible influence of chronic alterations in urine concentrating activity (CA) on renal hemodynamics, adult male Sprague-Dawley rats were submitted for 7 days to one of three different levels of CA. CA was either reduced by increasing water intake (mixing the food with a gel bringing 1.6 mL water per g food) (Low-CA), or increased by chronic intraperitoneal infusion of 1-desamino 8-D-arginine vasopressin (200 ng/day) (High-CA). Low-CA, High-CA, and control rats were housed in metabolic cages, ate the same quantity of dry food (the amount provided being slightly lower than the spontaneous intake), and had free access to drinking water. The only difference between groups thus concerned the water intake-vasopressin axis. Radiolabeled (14C)inulin was infused chronically by osmotic minipumps. Urine was collected during Days 5, 6, and 7, and blood samples were taken for determination of plasma composition (P), absolute and fractional (FE) urinary excretion, and clearance (C) of inulin, creatinine, urea, and main electrolytes. This protocol produced mean 24-h urine osmolality (Uosm) ranging from 500 to 3500 mosmol/kg H2O without inducing any disturbance in body fluids or plasma osmolality (Posm). Results show that GFR (Cinulin) was markedly and positively correlated with Uosm (r = 0.798, P < 0.001) and free water reabsorption (r = 0.819, P < 0.001). For Uosm = 2500 mosm/kg H2O, GFR was 47% higher than for Uosm = 500 mosm/kg H2O. Ccreat underestimated GFR in High-CA and overestimated it in Low-CA. FEurea was inversely related to Uosm, as expected from the increased reabsorption known to occur at low urine flows. It is tentatively proposed that the intrarenal recycling of urea, triggered by vasopressin and essential to the urinary concentrating mechanism, might influence GFR indirectly by modifying the composition of the tubular fluid at the macula densa and thus the intensity of the tubuloglomerular feedback control of GFR. Even if this mechanism remains to be confirmed, this study unequivocally demonstrates, in normal conscious rats, that the level of urinary concentrating activity has a major influence on basal GFR." @default.
• W1946571802 created "2016-06-24" @default.
• W1946571802 creator A5003063897 @default.
• W1946571802 creator A5012095540 @default.
• W1946571802 creator A5026204879 @default.
• W1946571802 creator A5055922720 @default.
• W1946571802 creator A5081461751 @default.
• W1946571802 creator A5086271385 @default.
• W1946571802 date "1996-06-01" @default.
• W1946571802 modified "2023-10-06" @default.
• W1946571802 title "Vasopressin increases glomerular filtration rate in conscious rats through its antidiuretic action." @default.
• W1946571802 cites W2020510806 @default.
• W1946571802 cites W2030202488 @default.
• W1946571802 cites W2031036560 @default.
• W1946571802 cites W2036789134 @default.
• W1946571802 cites W2064537324 @default.
• W1946571802 cites W2073651921 @default.
• W1946571802 cites W2473651725 @default.
• W1946571802 doi "https://doi.org/10.1681/asn.v76842" @default.
• W1946571802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8793792" @default.
• W1946571802 hasPublicationYear "1996" @default.
• W1946571802 type Work @default.
• W1946571802 sameAs 1946571802 @default.
• W1946571802 citedByCount "95" @default.
• W1946571802 countsByYear W19465718022012 @default.
• W1946571802 countsByYear W19465718022013 @default.
• W1946571802 countsByYear W19465718022014 @default.
• W1946571802 countsByYear W19465718022015 @default.
• W1946571802 countsByYear W19465718022016 @default.
• W1946571802 countsByYear W19465718022017 @default.
• W1946571802 countsByYear W19465718022018 @default.
• W1946571802 countsByYear W19465718022019 @default.
• W1946571802 countsByYear W19465718022020 @default.
• W1946571802 countsByYear W19465718022021 @default.
• W1946571802 countsByYear W19465718022022 @default.
• W1946571802 countsByYear W19465718022023 @default.
• W1946571802 crossrefType "journal-article" @default.
• W1946571802 hasAuthorship W1946571802A5003063897 @default.
• W1946571802 hasAuthorship W1946571802A5012095540 @default.
• W1946571802 hasAuthorship W1946571802A5026204879 @default.
• W1946571802 hasAuthorship W1946571802A5055922720 @default.
• W1946571802 hasAuthorship W1946571802A5081461751 @default.
• W1946571802 hasAuthorship W1946571802A5086271385 @default.
• W1946571802 hasBestOaLocation W19465718021 @default.
• W1946571802 hasConcept C10146269 @default.
• W1946571802 hasConcept C126322002 @default.
• W1946571802 hasConcept C134018914 @default.
• W1946571802 hasConcept C14705128 @default.
• W1946571802 hasConcept C159641895 @default.
• W1946571802 hasConcept C185592680 @default.
• W1946571802 hasConcept C2776370428 @default.
• W1946571802 hasConcept C2778534349 @default.
• W1946571802 hasConcept C2779420931 @default.
• W1946571802 hasConcept C2779547328 @default.
• W1946571802 hasConcept C2779742124 @default.
• W1946571802 hasConcept C2779805383 @default.
• W1946571802 hasConcept C2780026642 @default.
• W1946571802 hasConcept C2780091579 @default.
• W1946571802 hasConcept C2780306776 @default.
• W1946571802 hasConcept C2780762869 @default.
• W1946571802 hasConcept C33893070 @default.
• W1946571802 hasConcept C55493867 @default.
• W1946571802 hasConcept C56906281 @default.
• W1946571802 hasConcept C71924100 @default.
• W1946571802 hasConcept C7643261 @default.
• W1946571802 hasConceptScore W1946571802C10146269 @default.
• W1946571802 hasConceptScore W1946571802C126322002 @default.
• W1946571802 hasConceptScore W1946571802C134018914 @default.
• W1946571802 hasConceptScore W1946571802C14705128 @default.
• W1946571802 hasConceptScore W1946571802C159641895 @default.
• W1946571802 hasConceptScore W1946571802C185592680 @default.
• W1946571802 hasConceptScore W1946571802C2776370428 @default.
• W1946571802 hasConceptScore W1946571802C2778534349 @default.
• W1946571802 hasConceptScore W1946571802C2779420931 @default.
• W1946571802 hasConceptScore W1946571802C2779547328 @default.
• W1946571802 hasConceptScore W1946571802C2779742124 @default.
• W1946571802 hasConceptScore W1946571802C2779805383 @default.
• W1946571802 hasConceptScore W1946571802C2780026642 @default.
• W1946571802 hasConceptScore W1946571802C2780091579 @default.
• W1946571802 hasConceptScore W1946571802C2780306776 @default.
• W1946571802 hasConceptScore W1946571802C2780762869 @default.
• W1946571802 hasConceptScore W1946571802C33893070 @default.
• W1946571802 hasConceptScore W1946571802C55493867 @default.
• W1946571802 hasConceptScore W1946571802C56906281 @default.
• W1946571802 hasConceptScore W1946571802C71924100 @default.
• W1946571802 hasConceptScore W1946571802C7643261 @default.
• W1946571802 hasIssue "6" @default.
• W1946571802 hasLocation W19465718021 @default.
• W1946571802 hasOpenAccess W1946571802 @default.
• W1946571802 hasPrimaryLocation W19465718021 @default.
• W1946571802 hasRelatedWork W1946571802 @default.
• W1946571802 hasRelatedWork W1992092222 @default.
• W1946571802 hasRelatedWork W2003587549 @default.
• W1946571802 hasRelatedWork W2007843868 @default.
• W1946571802 hasRelatedWork W2057585929 @default.
• W1946571802 hasRelatedWork W2071155830 @default.
• W1946571802 hasRelatedWork W2089952601 @default.
• W1946571802 hasRelatedWork W2095548277 @default.

• next