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• W1946851022 abstract "Antioxidant, anti-Alzheimer and anti-inflammatory activities of enzymatic hydrolysates from Laminaria japonica were evaluated in this study. Four proteases (Protamex, Neutrase, Flavourzyme and Alcalase) and seven carbohydrases (Viscozyme, Celluclast, Dextrozyme, Amyloglucosidase [AMG], Promozyme, Termamyl and Maltogenase) were used in hydrolysis. Alcalase hydrolysate showed the highest total phenolic content, while Celluclast hydrolysate showed the highest total flavonoid content. 2,2-Diphenyl-1-Picrylhydrazyl radical scavenging activity was higher in Flavourzyme (78%) and Dextrozyme (79%) hydrolysates, hence selected for further antioxidant assays. Both, Flavourzyme and Dextrozyme hydrolysates showed strong activities in reducing power, metal chelating and hydrogen peroxide scavenging. Acetylcholinesterase inhibitory activity was higher in Flavourzyme hydrolysate (90%) and Celluclast (60%) hydrolysate. All hydrolysates showed more than 80% cell viability, while Protamex and AMG hydrolysates showed the highest activity in nitrite scavenging. The data suggested that L. japonica can be used as a potential natural source in food and pharmaceutical industries.PRATICAL APPLICATIONSIn this study, biological activities of enzymatic hydrolysates from Laminaria japonica were evaluated. The enzymatic hydrolysates exhibited various biological activities against antioxidant, anti-acetylcholinesterase and anti-inflammation. These results suggested that the enzymatic hydrolysates from L. japonica can be used as potential ingredient for functional food and/or pharmaceuticals." @default.
• W1946851022 created "2016-06-24" @default.
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• W1946851022 date "2011-12-12" @default.
• W1946851022 modified "2023-09-25" @default.
• W1946851022 title "EVALUATION OF ANTIOXIDANT, ANTI-ALZHEIMER'S AND ANTI-INFLAMMATORY ACTIVITIES OF ENZYMATIC HYDROLYSATES FROM EDIBLE BROWN SEAWEED (LAMINARIA JAPONICA)" @default.
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• W1946851022 doi "https://doi.org/10.1111/j.1745-4514.2010.00527.x" @default.
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