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• W1947127510 startingPage "21" @default.
• W1947127510 abstract "Stem cells are a promising alternative for cell therapy applications because of their self-renewing capability and potential to differentiate into a wide range of specialized cell lineages, including osteoblasts, chondrocytes, cardiomyocytes, and neuronal cells. Different kinds of stem cells are considered for cell-based tissue engineering approaches, of which bone-marrow-derived mesenchymal stem cells (BM-MSCs), adipose-derived stem cells (ADSCs) and embryonic stem cells (ESCs) are frequently utilized for advancement of new tissue engineering strategies. Nanostructures created by natural, synthetic, or composite polymeric biomaterials provide artificial templates of the extracellular matrix (ECM). They possess a high surface area to volume ratio, are porous with good mechanical properties, are sufficient to serve as a biomimetic platform to attract stem cells, cause differentiation, and provide functioning of the tissues. Nanoscale features such as fibers, pits, and grooves modulate cell behavior and might even stimulate the differentiation of stem cells to specific lineages; for example, the nanotopographical cues combined with chemical cues influence the neuronal induction of MSCs, resulting in high microtubule-associated protein expressions. Scaffolds can also be impregnated with several ligands for adhesion of receptors to the cells, or with other regulatory molecules and growth factors for designed cell behavior or controlled cell differentiations. Different polymeric blends or fibers incorporated with nanoparticles (such as hydroxyapatite) in aligned or custom-made patterns can induce specific differentiation of stem cells for bone, cartilage, cardiac, nerve, and skin tissue regeneration. In this review, we will discuss the current state of the art and future perspectives on stem cells and their differentiation on nanoengineered substrates for advanced tissue regeneration." @default.
• W1947127510 created "2016-06-24" @default.
• W1947127510 creator A5034165453 @default.
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• W1947127510 creator A5069662222 @default.
• W1947127510 creator A5074729253 @default.
• W1947127510 creator A5082642098 @default.
• W1947127510 date "2011-01-01" @default.
• W1947127510 modified "2023-09-23" @default.
• W1947127510 title "Stem Cells and Nanostructures for Advanced Tissue Regeneration" @default.
• W1947127510 cites W1544751778 @default.
• W1947127510 cites W1580484253 @default.
• W1947127510 cites W1605862014 @default.
• W1947127510 cites W1761485867 @default.
• W1947127510 cites W1877687712 @default.
• W1947127510 cites W1920534265 @default.
• W1947127510 cites W1942437020 @default.
• W1947127510 cites W1947347089 @default.
• W1947127510 cites W1964912726 @default.
• W1947127510 cites W1965045947 @default.
• W1947127510 cites W1966752515 @default.
• W1947127510 cites W1968450798 @default.
• W1947127510 cites W1968600918 @default.
• W1947127510 cites W1970037077 @default.
• W1947127510 cites W1970781687 @default.
• W1947127510 cites W1971265729 @default.
• W1947127510 cites W1971339046 @default.
• W1947127510 cites W1971628848 @default.
• W1947127510 cites W1972989180 @default.
• W1947127510 cites W1974207011 @default.
• W1947127510 cites W1974382774 @default.
• W1947127510 cites W1974388426 @default.
• W1947127510 cites W1974588738 @default.
• W1947127510 cites W1975712193 @default.
• W1947127510 cites W1976363654 @default.
• W1947127510 cites W1976628761 @default.
• W1947127510 cites W1976632391 @default.
• W1947127510 cites W1977253905 @default.
• W1947127510 cites W1978852166 @default.
• W1947127510 cites W1979086325 @default.
• W1947127510 cites W1979274462 @default.
• W1947127510 cites W1980070674 @default.
• W1947127510 cites W1982365233 @default.
• W1947127510 cites W1982397697 @default.
• W1947127510 cites W1983085571 @default.
• W1947127510 cites W1983308598 @default.
• W1947127510 cites W1983733906 @default.
• W1947127510 cites W1984417662 @default.
• W1947127510 cites W1985499103 @default.
• W1947127510 cites W1987032519 @default.
• W1947127510 cites W1987554991 @default.
• W1947127510 cites W1987957447 @default.
• W1947127510 cites W1988067509 @default.
• W1947127510 cites W1991472072 @default.
• W1947127510 cites W1992245888 @default.
• W1947127510 cites W1994410316 @default.
• W1947127510 cites W1994727098 @default.
• W1947127510 cites W1996867474 @default.
• W1947127510 cites W1996871478 @default.
• W1947127510 cites W1997552417 @default.
• W1947127510 cites W1998454830 @default.
• W1947127510 cites W2000623368 @default.
• W1947127510 cites W2001675896 @default.
• W1947127510 cites W2002207067 @default.
• W1947127510 cites W2003251092 @default.
• W1947127510 cites W2004443447 @default.
• W1947127510 cites W2004471754 @default.
• W1947127510 cites W2005307198 @default.
• W1947127510 cites W2005453584 @default.
• W1947127510 cites W2007004974 @default.
• W1947127510 cites W2008625423 @default.
• W1947127510 cites W2010984276 @default.
• W1947127510 cites W2011440234 @default.
• W1947127510 cites W2012282844 @default.
• W1947127510 cites W2013035509 @default.
• W1947127510 cites W2013277643 @default.
• W1947127510 cites W2013399275 @default.
• W1947127510 cites W2013969775 @default.
• W1947127510 cites W2014726972 @default.
• W1947127510 cites W2015367871 @default.
• W1947127510 cites W2015979204 @default.
• W1947127510 cites W2017041801 @default.
• W1947127510 cites W2017208938 @default.
• W1947127510 cites W2017522715 @default.
• W1947127510 cites W2018266638 @default.
• W1947127510 cites W2019071087 @default.
• W1947127510 cites W2021550972 @default.
• W1947127510 cites W2021634519 @default.
• W1947127510 cites W2021704166 @default.
• W1947127510 cites W2025824039 @default.
• W1947127510 cites W2025916992 @default.
• W1947127510 cites W2026271674 @default.
• W1947127510 cites W2026547102 @default.
• W1947127510 cites W2026760493 @default.
• W1947127510 cites W2026889973 @default.
• W1947127510 cites W2028036560 @default.
• W1947127510 cites W2030251993 @default.

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