Matches in SemOpenAlex for { <https://semopenalex.org/work/W1947460360> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W1947460360 endingPage "253" @default.
- W1947460360 startingPage "253" @default.
- W1947460360 abstract "Chromosomal aberrations in Allium cepa onion bulbs induced by 4-aminoquinoline hybrid molecules. Abstract. The toxicological properties of three hybrid compounds, quinoline-thiazolidinone (FR-72 and FR-121) and acridin-epoxyisoindolindione (FR-154) were studied by applying named compounds to the test of the roots of Allium cepa onion bulbs. Molecules FR-72, FR-121 and FR-154 were synthesized de novo according to described synthetic protocols. Clean and healthy bulbs of Allium cepa (2n = 16), previously immersed in distilled water, were dried with paper towels and placed directly into test tubes filled with the test substance. The experiments were carried out at room temperature 20 ± 2°C and were kept in darkness. The period of exposure of bulbs was 120 hours; the roots used for the genotoxicity evaluation were on average of 2 to 2.5 cm in length. The evaluation of the effect of the three quinolinic molecules on the growth of onion roots of Allium cepa bulbs was achieved using different concentrations of the three growth parameters (EC 50 , IM, ACs) The evaluated substances performed aneugenic actions, operating at cellular and molecular structure level and preventing the fixing of mitotic spindle fibers, causing the movement of chromosomes in the anaphase or loss of chromosomes, even inducing apoptosis by exceeding the homeostatic capacity of the cell. The preliminary analysis indicated that molecule FR- 121 at 10 -6 M concentration and molecule FR-154 at 10 -3 M concentration, proved to be potent phytotoxic agents causing various claustogenic and aneugenic aberrations." @default.
- W1947460360 created "2016-06-24" @default.
- W1947460360 creator A5052658531 @default.
- W1947460360 creator A5076168949 @default.
- W1947460360 creator A5077190919 @default.
- W1947460360 creator A5078705144 @default.
- W1947460360 creator A5083019784 @default.
- W1947460360 date "2012-12-14" @default.
- W1947460360 modified "2023-09-24" @default.
- W1947460360 title "Aberraciones cromosomales en bulbos de cebolla Allium cepa inducidas por moléculas híbridas 4-aminoquinolínicas" @default.
- W1947460360 cites W1512035040 @default.
- W1947460360 cites W1535416311 @default.
- W1947460360 cites W1583420249 @default.
- W1947460360 cites W1972372220 @default.
- W1947460360 cites W1984489322 @default.
- W1947460360 cites W1996877390 @default.
- W1947460360 cites W2024142650 @default.
- W1947460360 cites W2036291177 @default.
- W1947460360 cites W2037580435 @default.
- W1947460360 cites W2048816044 @default.
- W1947460360 cites W2068796659 @default.
- W1947460360 cites W2073357013 @default.
- W1947460360 cites W2079184250 @default.
- W1947460360 cites W2097630095 @default.
- W1947460360 cites W2100649767 @default.
- W1947460360 cites W2108673177 @default.
- W1947460360 cites W2136820833 @default.
- W1947460360 cites W2153021953 @default.
- W1947460360 cites W2217436801 @default.
- W1947460360 doi "https://doi.org/10.11144/javeriana.sc17-3.aceb" @default.
- W1947460360 hasPublicationYear "2012" @default.
- W1947460360 type Work @default.
- W1947460360 sameAs 1947460360 @default.
- W1947460360 citedByCount "7" @default.
- W1947460360 countsByYear W19474603602017 @default.
- W1947460360 countsByYear W19474603602019 @default.
- W1947460360 countsByYear W19474603602020 @default.
- W1947460360 countsByYear W19474603602022 @default.
- W1947460360 countsByYear W19474603602023 @default.
- W1947460360 crossrefType "journal-article" @default.
- W1947460360 hasAuthorship W1947460360A5052658531 @default.
- W1947460360 hasAuthorship W1947460360A5076168949 @default.
- W1947460360 hasAuthorship W1947460360A5077190919 @default.
- W1947460360 hasAuthorship W1947460360A5078705144 @default.
- W1947460360 hasAuthorship W1947460360A5083019784 @default.
- W1947460360 hasBestOaLocation W19474603601 @default.
- W1947460360 hasConcept C86803240 @default.
- W1947460360 hasConceptScore W1947460360C86803240 @default.
- W1947460360 hasIssue "3" @default.
- W1947460360 hasLocation W19474603601 @default.
- W1947460360 hasLocation W19474603602 @default.
- W1947460360 hasLocation W19474603603 @default.
- W1947460360 hasOpenAccess W1947460360 @default.
- W1947460360 hasPrimaryLocation W19474603601 @default.
- W1947460360 hasRelatedWork W1641042124 @default.
- W1947460360 hasRelatedWork W1990804418 @default.
- W1947460360 hasRelatedWork W1993764875 @default.
- W1947460360 hasRelatedWork W2013243191 @default.
- W1947460360 hasRelatedWork W2046158694 @default.
- W1947460360 hasRelatedWork W2082860237 @default.
- W1947460360 hasRelatedWork W2117258802 @default.
- W1947460360 hasRelatedWork W2130076355 @default.
- W1947460360 hasRelatedWork W2151865869 @default.
- W1947460360 hasRelatedWork W4234157524 @default.
- W1947460360 hasVolume "17" @default.
- W1947460360 isParatext "false" @default.
- W1947460360 isRetracted "false" @default.
- W1947460360 magId "1947460360" @default.
- W1947460360 workType "article" @default.