Matches in SemOpenAlex for { <https://semopenalex.org/work/W1947520754> ?p ?o ?g. }
- W1947520754 endingPage "1355" @default.
- W1947520754 startingPage "1346" @default.
- W1947520754 abstract "Herein, we report on the first enantioselective synthesis of the sparteine-type alkaloids virgidivarine (1) and virgiboidine (2). The stereoselective construction of the challenging dipiperidine core within 1 and 2 was realized by applying an intramolecular ene-ene-yne ring-rearrangement metathesis (RRM) protocol. In combination with this sequence, an unprecedented tandem metathesis/oxidation reaction was established. Subsequent to the RRM event, the Ru-alkylidene species was converted into the highly potent dihydroxylation catalyst RuO4 by the addition of NaIO4. This transformation rendered five sequential reactions that include an ene-ene-yne RRM/dihydroxylation/glycol cleavage in a one-pot procedure. This approach provides practical and general access to dipiperidines and piperidino-quinolizidines. Despite their wide use in organic and organometallic chemistry as well as their occurrence in biologically active natural products, methods are still lacking for the stereoselective synthesis of these motifs." @default.
- W1947520754 created "2016-06-24" @default.
- W1947520754 creator A5006106633 @default.
- W1947520754 creator A5032846636 @default.
- W1947520754 creator A5071704167 @default.
- W1947520754 creator A5088993005 @default.
- W1947520754 date "2013-01-17" @default.
- W1947520754 modified "2023-10-18" @default.
- W1947520754 title "Concise Total Syntheses of Dipiperidine Alkaloids Virgidivarine and Virgiboidine through Ru-Mediated Ene-Ene-Yne Ring Rearrangement Metathesis (RRM)" @default.
- W1947520754 cites W1967997540 @default.
- W1947520754 cites W1969003009 @default.
- W1947520754 cites W1970792173 @default.
- W1947520754 cites W1972972203 @default.
- W1947520754 cites W1974350112 @default.
- W1947520754 cites W1976231259 @default.
- W1947520754 cites W1982606890 @default.
- W1947520754 cites W1983931145 @default.
- W1947520754 cites W1990167275 @default.
- W1947520754 cites W1990819836 @default.
- W1947520754 cites W2000493966 @default.
- W1947520754 cites W2002159747 @default.
- W1947520754 cites W2010396621 @default.
- W1947520754 cites W2010693870 @default.
- W1947520754 cites W2012558007 @default.
- W1947520754 cites W2016764183 @default.
- W1947520754 cites W2019825607 @default.
- W1947520754 cites W2034826374 @default.
- W1947520754 cites W2040557992 @default.
- W1947520754 cites W2046177435 @default.
- W1947520754 cites W2047398912 @default.
- W1947520754 cites W2048796727 @default.
- W1947520754 cites W2049241660 @default.
- W1947520754 cites W2068695251 @default.
- W1947520754 cites W2071579008 @default.
- W1947520754 cites W2071972885 @default.
- W1947520754 cites W2073839523 @default.
- W1947520754 cites W2074998701 @default.
- W1947520754 cites W2086246324 @default.
- W1947520754 cites W2089161481 @default.
- W1947520754 cites W2095491031 @default.
- W1947520754 cites W2098455654 @default.
- W1947520754 cites W2099845816 @default.
- W1947520754 cites W2113032692 @default.
- W1947520754 cites W2119398944 @default.
- W1947520754 cites W2133994543 @default.
- W1947520754 cites W2136727502 @default.
- W1947520754 cites W2146107130 @default.
- W1947520754 cites W2150035767 @default.
- W1947520754 cites W2158559586 @default.
- W1947520754 cites W2167421903 @default.
- W1947520754 cites W2949351455 @default.
- W1947520754 cites W2950781885 @default.
- W1947520754 cites W2952577352 @default.
- W1947520754 cites W2952888329 @default.
- W1947520754 cites W2953176250 @default.
- W1947520754 cites W4240013171 @default.
- W1947520754 doi "https://doi.org/10.1002/ejoc.201201516" @default.
- W1947520754 hasPublicationYear "2013" @default.
- W1947520754 type Work @default.
- W1947520754 sameAs 1947520754 @default.
- W1947520754 citedByCount "21" @default.
- W1947520754 countsByYear W19475207542013 @default.
- W1947520754 countsByYear W19475207542014 @default.
- W1947520754 countsByYear W19475207542015 @default.
- W1947520754 countsByYear W19475207542016 @default.
- W1947520754 countsByYear W19475207542017 @default.
- W1947520754 countsByYear W19475207542018 @default.
- W1947520754 countsByYear W19475207542019 @default.
- W1947520754 countsByYear W19475207542020 @default.
- W1947520754 countsByYear W19475207542022 @default.
- W1947520754 crossrefType "journal-article" @default.
- W1947520754 hasAuthorship W1947520754A5006106633 @default.
- W1947520754 hasAuthorship W1947520754A5032846636 @default.
- W1947520754 hasAuthorship W1947520754A5071704167 @default.
- W1947520754 hasAuthorship W1947520754A5088993005 @default.
- W1947520754 hasConcept C146686406 @default.
- W1947520754 hasConcept C153914509 @default.
- W1947520754 hasConcept C161790260 @default.
- W1947520754 hasConcept C178790620 @default.
- W1947520754 hasConcept C181647583 @default.
- W1947520754 hasConcept C185592680 @default.
- W1947520754 hasConcept C21951064 @default.
- W1947520754 hasConcept C2777672777 @default.
- W1947520754 hasConcept C27777614 @default.
- W1947520754 hasConcept C35753019 @default.
- W1947520754 hasConcept C44138296 @default.
- W1947520754 hasConcept C44228677 @default.
- W1947520754 hasConcept C521977710 @default.
- W1947520754 hasConcept C71240020 @default.
- W1947520754 hasConceptScore W1947520754C146686406 @default.
- W1947520754 hasConceptScore W1947520754C153914509 @default.
- W1947520754 hasConceptScore W1947520754C161790260 @default.
- W1947520754 hasConceptScore W1947520754C178790620 @default.
- W1947520754 hasConceptScore W1947520754C181647583 @default.
- W1947520754 hasConceptScore W1947520754C185592680 @default.
- W1947520754 hasConceptScore W1947520754C21951064 @default.
- W1947520754 hasConceptScore W1947520754C2777672777 @default.
- W1947520754 hasConceptScore W1947520754C27777614 @default.