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- W1949281429 abstract "An attempt has been made to evaluate in the intact animal the effect of an inhibitor on a metabolic conversion. By the method employed it was found that the administration of sodium fluoroacetate (0.2 m M per kgm. of body weight) one-half hour before the injection of carboxyl-labeled acetate (10 m M per kgm. of body weight) resulted in a depression of the rate constant for the conversion of acetate to body CO2 to approximately 44 per cent of the values in unpoisoned mice. The rate of CO2 output was also drastically reduced by fluoroacetate. It is emphasized that the calculation of the rate constants involves many simplifying assumptions." @default.
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- W1949281429 date "1953-09-01" @default.
- W1949281429 modified "2023-09-23" @default.
- W1949281429 title "Effect of fluoroacetate on the conversion of isotopic acetate to carbon dioxide by the mouse." @default.
- W1949281429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/13097328" @default.
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