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- W194997683 abstract "By occluding the bilateral carotid arteries of rabbits to produce bilateral partial cerebral ischemia, and by using radioimmunoassays to measure the levels of dynorphin A1-13 like immunoreactivity (ir-Dyn A1-13) in plasma and cerebrospinal fluid (CSF), the authors find that the levels of ir-Dyn A1-13 in plasma and CSF have significantly increased (P less than 0.01) after cerebral ischemia appears. The result of the Ligusticum wallichii Franch (Ligusticum) pretreatment to the test-group shows a definite improvement of the changes of ir-Dyn A1-13 levels in plasma and CSF. The severity of brain ischemic damage and neurologic dysfunction in Ligusticum-treated animals is lighter than that of saline-treated group, too. In this study, some new approaches are explored to explain the pathophysiology of cerebral ischemia and the mechanisms by which Ligusticum prevents and treats cerebral ischemia." @default.
- W194997683 created "2016-06-24" @default.
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- W194997683 date "1990-03-01" @default.
- W194997683 modified "2023-10-18" @default.
- W194997683 title "[Effects of Ligusticum wallichii on the plasma and CSF levels of dynorphin A1-13 in rabbits under acute experimental cerebral ischemia]." @default.
- W194997683 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1974173" @default.
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