Matches in SemOpenAlex for { <https://semopenalex.org/work/W1950130858> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1950130858 endingPage "12" @default.
- W1950130858 startingPage "7" @default.
- W1950130858 abstract "Abstract Episomal plasmids (p8901) with minigenes coding for the influenza virus matrix peptide amino acids 57-68 (KGILGFVFTLTV; referred to as M57-68) or coding for a modified peptide were introduced into HLA-A2-positive target cells. The association of these peptides, synthesized in the cytoplasm, with HLA-A2 and the expression of this complex at the cell surface was evaluated with HLA-A2-restricted CTL specific for the influenza virus matrix peptide M57-68. Cells expressing M57-68 were lysed effectively, as were cells expressing a peptide that retained residues 60-64 with seven flanking alanine residues (AAALGFVFAAAA). An exogenously added synthetic analog of peptide M57-68 that inhibited sensitization of targets with synthetic peptide M57-68 also inhibited lysis of cells expressing the minigene coding for the peptide with seven alanine substitutions. These results demonstrate the utility of minigene DNA constructs in creating experimental systems to develop agents to diminish the severity of CTL-mediated tissue damage in autoimmune diseases and graft rejection." @default.
- W1950130858 created "2016-06-24" @default.
- W1950130858 creator A5007731432 @default.
- W1950130858 creator A5020300899 @default.
- W1950130858 creator A5038619028 @default.
- W1950130858 creator A5050404652 @default.
- W1950130858 creator A5053085069 @default.
- W1950130858 creator A5059291228 @default.
- W1950130858 creator A5071008903 @default.
- W1950130858 creator A5082221306 @default.
- W1950130858 date "1992-01-01" @default.
- W1950130858 modified "2023-10-11" @default.
- W1950130858 title "Endogenous loading of HLA-A2 molecules with an analog of the influenza virus matrix protein-derived peptide and its inhibition by an exogenous peptide antagonist." @default.
- W1950130858 doi "https://doi.org/10.4049/jimmunol.148.1.7" @default.
- W1950130858 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1727876" @default.
- W1950130858 hasPublicationYear "1992" @default.
- W1950130858 type Work @default.
- W1950130858 sameAs 1950130858 @default.
- W1950130858 citedByCount "6" @default.
- W1950130858 countsByYear W19501308582017 @default.
- W1950130858 crossrefType "journal-article" @default.
- W1950130858 hasAuthorship W1950130858A5007731432 @default.
- W1950130858 hasAuthorship W1950130858A5020300899 @default.
- W1950130858 hasAuthorship W1950130858A5038619028 @default.
- W1950130858 hasAuthorship W1950130858A5050404652 @default.
- W1950130858 hasAuthorship W1950130858A5053085069 @default.
- W1950130858 hasAuthorship W1950130858A5059291228 @default.
- W1950130858 hasAuthorship W1950130858A5071008903 @default.
- W1950130858 hasAuthorship W1950130858A5082221306 @default.
- W1950130858 hasBestOaLocation W19501308581 @default.
- W1950130858 hasConcept C104317684 @default.
- W1950130858 hasConcept C10858879 @default.
- W1950130858 hasConcept C147483822 @default.
- W1950130858 hasConcept C147969180 @default.
- W1950130858 hasConcept C153911025 @default.
- W1950130858 hasConcept C154317977 @default.
- W1950130858 hasConcept C159047783 @default.
- W1950130858 hasConcept C166342232 @default.
- W1950130858 hasConcept C167625842 @default.
- W1950130858 hasConcept C195616568 @default.
- W1950130858 hasConcept C202751555 @default.
- W1950130858 hasConcept C203014093 @default.
- W1950130858 hasConcept C22744801 @default.
- W1950130858 hasConcept C2522874641 @default.
- W1950130858 hasConcept C2777546802 @default.
- W1950130858 hasConcept C2779281246 @default.
- W1950130858 hasConcept C54458228 @default.
- W1950130858 hasConcept C552990157 @default.
- W1950130858 hasConcept C55493867 @default.
- W1950130858 hasConcept C67705224 @default.
- W1950130858 hasConcept C68434959 @default.
- W1950130858 hasConcept C86803240 @default.
- W1950130858 hasConceptScore W1950130858C104317684 @default.
- W1950130858 hasConceptScore W1950130858C10858879 @default.
- W1950130858 hasConceptScore W1950130858C147483822 @default.
- W1950130858 hasConceptScore W1950130858C147969180 @default.
- W1950130858 hasConceptScore W1950130858C153911025 @default.
- W1950130858 hasConceptScore W1950130858C154317977 @default.
- W1950130858 hasConceptScore W1950130858C159047783 @default.
- W1950130858 hasConceptScore W1950130858C166342232 @default.
- W1950130858 hasConceptScore W1950130858C167625842 @default.
- W1950130858 hasConceptScore W1950130858C195616568 @default.
- W1950130858 hasConceptScore W1950130858C202751555 @default.
- W1950130858 hasConceptScore W1950130858C203014093 @default.
- W1950130858 hasConceptScore W1950130858C22744801 @default.
- W1950130858 hasConceptScore W1950130858C2522874641 @default.
- W1950130858 hasConceptScore W1950130858C2777546802 @default.
- W1950130858 hasConceptScore W1950130858C2779281246 @default.
- W1950130858 hasConceptScore W1950130858C54458228 @default.
- W1950130858 hasConceptScore W1950130858C552990157 @default.
- W1950130858 hasConceptScore W1950130858C55493867 @default.
- W1950130858 hasConceptScore W1950130858C67705224 @default.
- W1950130858 hasConceptScore W1950130858C68434959 @default.
- W1950130858 hasConceptScore W1950130858C86803240 @default.
- W1950130858 hasIssue "1" @default.
- W1950130858 hasLocation W19501308581 @default.
- W1950130858 hasLocation W19501308582 @default.
- W1950130858 hasOpenAccess W1950130858 @default.
- W1950130858 hasPrimaryLocation W19501308581 @default.
- W1950130858 hasRelatedWork W1607711284 @default.
- W1950130858 hasRelatedWork W1950130858 @default.
- W1950130858 hasRelatedWork W1965399968 @default.
- W1950130858 hasRelatedWork W1966248592 @default.
- W1950130858 hasRelatedWork W2012280098 @default.
- W1950130858 hasRelatedWork W2049985206 @default.
- W1950130858 hasRelatedWork W2052483994 @default.
- W1950130858 hasRelatedWork W2072706651 @default.
- W1950130858 hasRelatedWork W2157252414 @default.
- W1950130858 hasRelatedWork W4232045806 @default.
- W1950130858 hasVolume "148" @default.
- W1950130858 isParatext "false" @default.
- W1950130858 isRetracted "false" @default.
- W1950130858 magId "1950130858" @default.
- W1950130858 workType "article" @default.