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• W1950850293 abstract "Metergoline, a serotonin receptor antagonist, was evaluated for its antifungal activity against the opportunistic human fungal pathogen Candida krusei by a broth microdilution assay. The minimal inhibitory concentration and minimal fungicidal concentration of metergoline against C. krusei were 4 and 8 μg ml(-1) respectively. Significant synergism was found in combination of metergoline with amphotericin B (fractional inhibitory concentration index: 0.375-0.5) by a chequerboard assay. Metergoline also inhibited extracellular phospholipase secretion in a dose-dependent manner, which may be a possible action mechanism of metergoline on C. krusei." @default.
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• W1950850293 date "2009-06-15" @default.
• W1950850293 modified "2023-10-01" @default.
• W1950850293 title "In vitro synergistic effects of metergoline and antifungal agents against Candida krusei" @default.
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• W1950850293 doi "https://doi.org/10.1111/j.1439-0507.2009.01747.x" @default.
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