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- W1951551184 abstract "Abstract The development of IgG PFC responses specific for the random terpolymer of l-glutamic acid60-l-alanine30-L-tyrosine10 (GAT) by virgin and immune (responder C57BL/10 × nonresponder DBA/1)F1 spleen cells after stimulation with responder and nonresponder parental or F1 GAT-pulsed macrophages (GAT/Mϕ) in vitro was investigated. Virgin F1 spleen cells developed comparable primary responses to GAT-MBSA and to both parental and F1 GAT-Mϕ. F1 spleen cells from mice immunized with responder or nonresponder parental GAT-Mϕ developed secondary responses only after stimulation with the parental GAT-Mϕ used for immunization or F1 GAT-Mϕ. These observations are consistent with previous observations that spleen cells from mice immunized with syngeneic or allogeneic GAT-Mϕ develop secondary responses only with GAT-Mϕ syngeneic at the I-A subregion of the H-2 complex with the M-ϕ used for priming. By contrast, F1 spleen cells from mice immunized with GAT-MBSA or F1 GAT-Mϕ developed secondary responses after stimulation with either parental or F1 GAT-Mϕ." @default.
- W1951551184 created "2016-06-24" @default.
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- W1951551184 date "1978-10-01" @default.
- W1951551184 modified "2023-09-25" @default.
- W1951551184 title "Antibody Responses to GAT by (Responder × Nonresponder)F1 Spleen Cells Stimulated by Parental GAT-Macrophages" @default.
- W1951551184 doi "https://doi.org/10.4049/jimmunol.121.4.1616.b" @default.
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