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- W1951976295 abstract "Veratridine, injected in single (0.05 to 2 mg) or repeated doses or infused at various rates, caused the well-known positive inotropic effect, measured by the strain-gauge arch, in nonfailing heart-lung preparations. This effect was associated with either a gain or a loss of cardiac potassium, as measured within 90 seconds after the injection. The loss occurred with larger doses (0.4 mg or more) and was associated with (but sometimes preceded) ventricular irregularities or ventricular tachycardia. The gain occurred with 3 out of 7 smaller single doses(0.05 to 0.4 mg) and was successively increased by successive small doses, or increased progressively with infusions at suitable rates. Either the gain or the loss could reach 15 µg per minute per 100 g wet heart weight." @default.
- W1951976295 created "2016-06-24" @default.
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- W1951976295 date "1961-11-01" @default.
- W1951976295 modified "2023-09-26" @default.
- W1951976295 title "Effects of veratridine on the potassium balance of the dog heart-lung preparation." @default.
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- W1951976295 hasPublicationYear "1961" @default.
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