Matches in SemOpenAlex for { <https://semopenalex.org/work/W1952510189> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W1952510189 endingPage "295" @default.
- W1952510189 startingPage "289" @default.
- W1952510189 abstract "Chronic arsenic exposure can lead to palmoplantar keratosis. In the stratum corneum of skin, linoleic acid is of the utmost importance to the inflammation, keratinization, and regeneration processes.The aims of this study were: (i) to present quantitative information on the linoleic acid fraction of intercorneocyte lipids, and (ii) to elucidate the role of linoleic acid in the pathophysiology of arsenical keratosis.Lipid extracts were collected from keratotic lesions in seven patients, seven arsenic-exposed subjects, and seven non-exposed control subjects. Linoleic acid levels of the specimens were estimated by reverse-phase high-performance liquid chromatography (RP-HPLC).There was a significant (P < 0.001) increase in mean ± standard error (SE) linoleic acid levels in arsenical keratosis patients (palm: 25.66 ± 4.95 μg/cm(2); dorsum: 28.25 ± 6.20 μg/cm(2)) compared with arsenic-exposed (palm: 2.75 ± 0.85 μg/cm(2); dorsum: 1.96 ± 0.64 μg/cm(2)) and non-exposed (palm: 1.52 ± 0.61 μg/cm(2); dorsum: 1.28 ± 0.39 μg/cm(2)) control subjects. There was no significant difference (P = 0.556) in linoleic acid concentration in the non-affected skin of the dorsum of the hand (28.25 ± 6.20 μg/cm(2)) compared with that in the palmar sites (25.66 ± 4.95 μg/cm(2)) in the patient group. The change in linoleic acid levels in the arsenic-exposed control group did not differ from that in non-exposed controls (P = 1.000).Linoleic acid concentration is elevated in arsenical keratosis; this finding warrants further investigation to ascertain whether linoleic acid plays a direct role in the pathophysiology of arsenical keratosis." @default.
- W1952510189 created "2016-06-24" @default.
- W1952510189 creator A5016085568 @default.
- W1952510189 creator A5054507750 @default.
- W1952510189 date "2015-07-31" @default.
- W1952510189 modified "2023-09-24" @default.
- W1952510189 title "Role of linoleic acid in arsenical palmar keratosis" @default.
- W1952510189 cites W1018251664 @default.
- W1952510189 cites W1990602116 @default.
- W1952510189 cites W2018223387 @default.
- W1952510189 cites W2024462477 @default.
- W1952510189 cites W2030178194 @default.
- W1952510189 cites W2037601794 @default.
- W1952510189 cites W2059890696 @default.
- W1952510189 cites W2083563689 @default.
- W1952510189 cites W2096526406 @default.
- W1952510189 cites W2121512138 @default.
- W1952510189 cites W2122708367 @default.
- W1952510189 cites W2151330444 @default.
- W1952510189 cites W2154409359 @default.
- W1952510189 cites W2160758815 @default.
- W1952510189 cites W2163666912 @default.
- W1952510189 cites W2169484065 @default.
- W1952510189 cites W2181991802 @default.
- W1952510189 cites W2254910540 @default.
- W1952510189 cites W4237083635 @default.
- W1952510189 doi "https://doi.org/10.1111/ijd.12831" @default.
- W1952510189 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26235890" @default.
- W1952510189 hasPublicationYear "2015" @default.
- W1952510189 type Work @default.
- W1952510189 sameAs 1952510189 @default.
- W1952510189 citedByCount "2" @default.
- W1952510189 countsByYear W19525101892016 @default.
- W1952510189 countsByYear W19525101892017 @default.
- W1952510189 crossrefType "journal-article" @default.
- W1952510189 hasAuthorship W1952510189A5016085568 @default.
- W1952510189 hasAuthorship W1952510189A5054507750 @default.
- W1952510189 hasConcept C105702510 @default.
- W1952510189 hasConcept C140530291 @default.
- W1952510189 hasConcept C16005928 @default.
- W1952510189 hasConcept C185592680 @default.
- W1952510189 hasConcept C2778648961 @default.
- W1952510189 hasConcept C2780809830 @default.
- W1952510189 hasConcept C31903555 @default.
- W1952510189 hasConcept C543025807 @default.
- W1952510189 hasConcept C55493867 @default.
- W1952510189 hasConcept C71924100 @default.
- W1952510189 hasConceptScore W1952510189C105702510 @default.
- W1952510189 hasConceptScore W1952510189C140530291 @default.
- W1952510189 hasConceptScore W1952510189C16005928 @default.
- W1952510189 hasConceptScore W1952510189C185592680 @default.
- W1952510189 hasConceptScore W1952510189C2778648961 @default.
- W1952510189 hasConceptScore W1952510189C2780809830 @default.
- W1952510189 hasConceptScore W1952510189C31903555 @default.
- W1952510189 hasConceptScore W1952510189C543025807 @default.
- W1952510189 hasConceptScore W1952510189C55493867 @default.
- W1952510189 hasConceptScore W1952510189C71924100 @default.
- W1952510189 hasIssue "3" @default.
- W1952510189 hasLocation W19525101891 @default.
- W1952510189 hasLocation W19525101892 @default.
- W1952510189 hasOpenAccess W1952510189 @default.
- W1952510189 hasPrimaryLocation W19525101891 @default.
- W1952510189 hasRelatedWork W2347508298 @default.
- W1952510189 hasRelatedWork W2354496245 @default.
- W1952510189 hasRelatedWork W2355475018 @default.
- W1952510189 hasRelatedWork W3030876802 @default.
- W1952510189 hasRelatedWork W3032740034 @default.
- W1952510189 hasVolume "55" @default.
- W1952510189 isParatext "false" @default.
- W1952510189 isRetracted "false" @default.
- W1952510189 magId "1952510189" @default.
- W1952510189 workType "article" @default.