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- W195260386 abstract "We describe the morpho-functional effects of different concentrations of okadaic acid (OA) onspecimens of Enchytraeus crypticus. The results demonstrate that this experimental model is verysensitive to the treatment and presents time- and dose-related effects mainly involving an immuneresponse associated with a reaction in the chloragogenous tissue. At the lower dose (100 nM), themain organs do not appear particularly affected except for a swelling of the coelomatic cavity and anincreased number of circulating coelomocytes. At the higher dose (200 nM), the chloragogenoustissue extends in volume to occupy the body cavity almost completely, while the circulatingamoebocytes and chloragocytic cells undergo conformational changes. At the highest OA dose (400nM), there is a general cell suffering in the main animal organs. In control animals, theimmunocytochemical reaction with anti-IL-6 antibody is positive in neuron cell bodies and fibres fromthe ventral nerve cord and in circulating amoebocytes. Following OA treatment, fewer immunoreactive cells are seen in the damaged nervous tissue, and the high number of recruited amoebocytes is also positive." @default.
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- W195260386 date "2006-11-29" @default.
- W195260386 modified "2023-09-23" @default.
- W195260386 title "The effects of okadaic acid on Enchytraeus crypticus (Annelida: Oligochaeta)" @default.
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