FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1952607842> ?p ?o ?g. }

• W1952607842 abstract "Although significant progress has been made in the treatment of HIV infection, we are still far from wining the battle. The combination of highly active antiretroviral therapy (HAART) in compliant patients comes close to stopping virus evolution; however, eradication of the infection has not been achieved because of the persistence of latent HIV-1 in resting memory CD4+ T cells. Moreover, several factors including the emergence of multidrug-resistant HIV strains, drug toxicity, the patient's ability to adhere to the prescribed therapy, and expensive medication have necessitated a reason to develop novel drugs and novel approaches to combat HIV infection. Currently, the HAART regimen consists of nucleoside and nonnucleoside reverse transcriptase (RT) combined with protease (PR) inhibitors. This article summarizes all currently approved drugs for HIV-1 infection as well as drugs that have made significant progress in clinical trials but have not yet been approved. Where appropriate, their mechanism of action, mechanism of resistance, and toxicity are discussed" @default.
• W1952607842 created "2016-06-24" @default.
• W1952607842 creator A5023220693 @default.
• W1952607842 creator A5043997105 @default.
• W1952607842 date "2006-09-15" @default.
• W1952607842 modified "2023-10-18" @default.
• W1952607842 title "HIV Therapeutics, Biochemistry of" @default.
• W1952607842 cites W1482773835 @default.
• W1952607842 cites W1503253993 @default.
• W1952607842 cites W1548955637 @default.
• W1952607842 cites W1628484047 @default.
• W1952607842 cites W1851109692 @default.
• W1952607842 cites W1965019797 @default.
• W1952607842 cites W1966293314 @default.
• W1952607842 cites W1966952510 @default.
• W1952607842 cites W1971758177 @default.
• W1952607842 cites W1972056955 @default.
• W1952607842 cites W1974224443 @default.
• W1952607842 cites W1976011820 @default.
• W1952607842 cites W1976787212 @default.
• W1952607842 cites W1978444406 @default.
• W1952607842 cites W1978902758 @default.
• W1952607842 cites W1980437255 @default.
• W1952607842 cites W1983066351 @default.
• W1952607842 cites W1984380553 @default.
• W1952607842 cites W1984811742 @default.
• W1952607842 cites W1985772041 @default.
• W1952607842 cites W1987688509 @default.
• W1952607842 cites W1988002070 @default.
• W1952607842 cites W1989035987 @default.
• W1952607842 cites W1995396220 @default.
• W1952607842 cites W1998859554 @default.
• W1952607842 cites W2001113321 @default.
• W1952607842 cites W2002701698 @default.
• W1952607842 cites W2003550508 @default.
• W1952607842 cites W2017436619 @default.
• W1952607842 cites W2018348496 @default.
• W1952607842 cites W2018435896 @default.
• W1952607842 cites W2021932640 @default.
• W1952607842 cites W2024600963 @default.
• W1952607842 cites W2025430406 @default.
• W1952607842 cites W2027095884 @default.
• W1952607842 cites W2028309086 @default.
• W1952607842 cites W2028643246 @default.
• W1952607842 cites W2033978085 @default.
• W1952607842 cites W2046134251 @default.
• W1952607842 cites W2048336729 @default.
• W1952607842 cites W2052157498 @default.
• W1952607842 cites W2052200516 @default.
• W1952607842 cites W2054728806 @default.
• W1952607842 cites W2055377707 @default.
• W1952607842 cites W2055542167 @default.
• W1952607842 cites W2059794436 @default.
• W1952607842 cites W2059900269 @default.
• W1952607842 cites W2065631521 @default.
• W1952607842 cites W2065740427 @default.
• W1952607842 cites W2066074388 @default.
• W1952607842 cites W2076989459 @default.
• W1952607842 cites W2077857538 @default.
• W1952607842 cites W2080786231 @default.
• W1952607842 cites W2081769332 @default.
• W1952607842 cites W2083612980 @default.
• W1952607842 cites W2084702672 @default.
• W1952607842 cites W2089019538 @default.
• W1952607842 cites W2089249230 @default.
• W1952607842 cites W2089882643 @default.
• W1952607842 cites W2090630729 @default.
• W1952607842 cites W2094115571 @default.
• W1952607842 cites W2094180923 @default.
• W1952607842 cites W2096649016 @default.
• W1952607842 cites W2098781795 @default.
• W1952607842 cites W2099782613 @default.
• W1952607842 cites W2102098015 @default.
• W1952607842 cites W2103509386 @default.
• W1952607842 cites W2109604183 @default.
• W1952607842 cites W2110838631 @default.
• W1952607842 cites W2112129496 @default.
• W1952607842 cites W2112857740 @default.
• W1952607842 cites W2114679297 @default.
• W1952607842 cites W2117394497 @default.
• W1952607842 cites W2119855246 @default.
• W1952607842 cites W2120296634 @default.
• W1952607842 cites W2122944706 @default.
• W1952607842 cites W2123166384 @default.
• W1952607842 cites W2123581489 @default.
• W1952607842 cites W2126067457 @default.
• W1952607842 cites W2126431223 @default.
• W1952607842 cites W2127137755 @default.
• W1952607842 cites W2130082288 @default.
• W1952607842 cites W2131376910 @default.
• W1952607842 cites W2132185205 @default.
• W1952607842 cites W2137558037 @default.
• W1952607842 cites W2140129347 @default.
• W1952607842 cites W2142144836 @default.
• W1952607842 cites W2143773220 @default.
• W1952607842 cites W2146777881 @default.
• W1952607842 cites W2162324851 @default.
• W1952607842 cites W2165253161 @default.
• W1952607842 cites W2165732545 @default.
• W1952607842 cites W2170412417 @default.

• next