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- W1953919005 abstract "The sigma (σ)-subunit of bacterial RNA polymerase (RNAP) is essential for the process of promoter selection. Interactions between σ and promoter region DNA allow RNAP to recognize and physically open the start sites for transcription initiation. The majority of transcription under most conditions requires a single, essential σ-factor (primary σ). However, in most bacteria, there are a number of alternative σ-factors that can activate specific sets of target genes, as defined by their distinct promoter sequences, in response to changing environmental conditions. The activation of groups of coregulated genes (regulons) by alternative σ-factors complements the more familiar gene-regulation mechanisms that rely upon transcription repressors and activators." @default.
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- W1953919005 date "1995-02-01" @default.
- W1953919005 modified "2023-09-25" @default.
- W1953919005 title "Genetics of bacterial virulence by Charles J. Dorman, Blackwell Scientific Publications, 1994, £29.50 (xix + 369 pages) ISBN O 632 03662 1" @default.
- W1953919005 doi "https://doi.org/10.1016/s0968-0004(00)88968-9" @default.
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