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• W1954021944 abstract "To help gain a better understanding of factors influencing the establishment within the oral cavity of Streptococcus salivarius K12, a commensal oral bacterium, we characterized its behaviour in artificial saliva.Streptococcus salivarius K12 was grown in artificial saliva complemented with a representative meal, under oral pH and temperature conditions. Exponential growth phase was characterized by a high specific growth rate (2.8 h(-1)). During maintenance phase, an uncoupling between growth and lactic acid production occurred, which allowed maintaining viability (95%), intracellular pH (6.6) and membrane polarisation (95%), and thus proton motive force. However, in late stationary phase, viability (64%) and vitality were degraded as a result of lower synthesis of energetic and glycogen-related proteins as compared to a richer medium.Streptococcus salivarius was able to rapidly grow in complemented artificial saliva. Nevertheless, a degradation of its physiological state was observed in late-stationary phase.This work demonstrates, for the first time, that artificial saliva was a convenient medium that permitted Strep. salivarius to grow in oral conditions (physico-chemical environment, addition of meals) but not to maintain cellular viability and vitality in starvation conditions." @default.
• W1954021944 created "2016-06-24" @default.
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• W1954021944 creator A5077195243 @default.
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• W1954021944 date "2011-07-18" @default.
• W1954021944 modified "2023-09-27" @default.
• W1954021944 title "Characterization of Streptococcus salivarius growth and maintenance in artificial saliva" @default.
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• W1954021944 doi "https://doi.org/10.1111/j.1365-2672.2011.05077.x" @default.
• W1954021944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21672100" @default.
• W1954021944 hasPublicationYear "2011" @default.
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