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- W1954338004 abstract "Ten per cent carbon dioxide was administered acutely to anesthetized 15–20-kg dogs which had been loaded with varying quantities of hypertonic NaCl, hypertonic NaHCO 3 and, in some experiments, urea. In animals with low blood concentration and excretion rates of bicarbonate, CO 2 had no effect on sodium chloride reabsorption as measured at constant creatinine clearance. In animals with normal or elevated blood concentration together with significant excretion rates of bicarbonate, CO 2 resulted in a 5–7% increase in sodium chloride reabsorption. The effect on reabsorption was greater than predicted on the assumption that bicarbonate had depressed chloride reabsorption by acting as a simple osmotic diuretic and that CO 2 , by enhancing bicarbonate reabsorption, had removed some of this osmotic diuretic agent." @default.
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- W1954338004 date "1959-02-28" @default.
- W1954338004 modified "2023-10-18" @default.
- W1954338004 title "Effects of acute elevation of blood CO2 tension on renal excretion of chloride and sodium by the anesthetized dog" @default.
- W1954338004 doi "https://doi.org/10.1152/ajplegacy.1959.196.3.529" @default.
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