FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1957753312> ?p ?o ?g. }

• W1957753312 endingPage "4096" @default.
• W1957753312 startingPage "4090" @default.
• W1957753312 abstract "Human isolates of dengue (DEN) type 1 viruses FGA/89 and BR/90 differ in their membrane fusion properties in mosquito cell lines (P. Desprès et al., Virology 196:209-216, 1993). FGA/89 and BR/90 were assayed for their neurovirulence in newborn mice, and neurons were the major target cells for both DEN-1 virus strains within the central nervous system. To study the susceptibility of neurons to DEN virus infection, DEN virus replication was analyzed in the murine neuroblastoma cell line Neuro 2a. Infection of Neuro 2a cells with FGA/89 or BR/90 induced apoptotic DNA degradation after 25 h of infection. Studies of DEN protein synthesis revealed that accumulation of viral proteins leads to apoptotic cell death. The apoptotic process progressed more rapidly following BR/90 infection than it did after FGA/89 infection. The higher cytotoxicity of BR/90 for Neuro 2a cells was linked to an incomplete maturation of the envelope proteins, resulting in abortive virus assembly. Accumulation of viral proteins in the endoplasmic reticulum may induce stress and thereby activate the apoptotic pathway in mouse neuroblastoma cells." @default.
• W1957753312 created "2016-06-24" @default.
• W1957753312 creator A5008504422 @default.
• W1957753312 creator A5014294436 @default.
• W1957753312 creator A5022532108 @default.
• W1957753312 creator A5082521577 @default.
• W1957753312 date "1996-06-01" @default.
• W1957753312 modified "2023-10-18" @default.
• W1957753312 title "Human isolates of dengue type 1 virus induce apoptosis in mouse neuroblastoma cells" @default.
• W1957753312 cites W1470758466 @default.
• W1957753312 cites W1527726281 @default.
• W1957753312 cites W1538805645 @default.
• W1957753312 cites W1568529372 @default.
• W1957753312 cites W1577403013 @default.
• W1957753312 cites W1912434761 @default.
• W1957753312 cites W1967931960 @default.
• W1957753312 cites W1969185143 @default.
• W1957753312 cites W1978035722 @default.
• W1957753312 cites W1999525967 @default.
• W1957753312 cites W2011371104 @default.
• W1957753312 cites W2036145275 @default.
• W1957753312 cites W2037044371 @default.
• W1957753312 cites W2040112003 @default.
• W1957753312 cites W2042251173 @default.
• W1957753312 cites W2051070266 @default.
• W1957753312 cites W2078001244 @default.
• W1957753312 cites W2078046758 @default.
• W1957753312 cites W2081145901 @default.
• W1957753312 cites W2084223366 @default.
• W1957753312 cites W2084261874 @default.
• W1957753312 cites W2085820606 @default.
• W1957753312 cites W2124483903 @default.
• W1957753312 cites W2128696674 @default.
• W1957753312 cites W2138302361 @default.
• W1957753312 cites W2139970952 @default.
• W1957753312 cites W2140369997 @default.
• W1957753312 cites W2165117243 @default.
• W1957753312 cites W2470208181 @default.
• W1957753312 cites W43967522 @default.
• W1957753312 doi "https://doi.org/10.1128/jvi.70.6.4090-4096.1996" @default.
• W1957753312 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/190291" @default.
• W1957753312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8648748" @default.
• W1957753312 hasPublicationYear "1996" @default.
• W1957753312 type Work @default.
• W1957753312 sameAs 1957753312 @default.
• W1957753312 citedByCount "109" @default.
• W1957753312 countsByYear W19577533122012 @default.
• W1957753312 countsByYear W19577533122013 @default.
• W1957753312 countsByYear W19577533122014 @default.
• W1957753312 countsByYear W19577533122015 @default.
• W1957753312 countsByYear W19577533122016 @default.
• W1957753312 countsByYear W19577533122017 @default.
• W1957753312 countsByYear W19577533122018 @default.
• W1957753312 countsByYear W19577533122019 @default.
• W1957753312 countsByYear W19577533122021 @default.
• W1957753312 countsByYear W19577533122022 @default.
• W1957753312 crossrefType "journal-article" @default.
• W1957753312 hasAuthorship W1957753312A5008504422 @default.
• W1957753312 hasAuthorship W1957753312A5014294436 @default.
• W1957753312 hasAuthorship W1957753312A5022532108 @default.
• W1957753312 hasAuthorship W1957753312A5082521577 @default.
• W1957753312 hasBestOaLocation W19577533121 @default.
• W1957753312 hasConcept C140704245 @default.
• W1957753312 hasConcept C153911025 @default.
• W1957753312 hasConcept C158617107 @default.
• W1957753312 hasConcept C159047783 @default.
• W1957753312 hasConcept C190283241 @default.
• W1957753312 hasConcept C2522874641 @default.
• W1957753312 hasConcept C2776715637 @default.
• W1957753312 hasConcept C2779635636 @default.
• W1957753312 hasConcept C31573885 @default.
• W1957753312 hasConcept C54355233 @default.
• W1957753312 hasConcept C55493867 @default.
• W1957753312 hasConcept C81885089 @default.
• W1957753312 hasConcept C82210918 @default.
• W1957753312 hasConcept C86803240 @default.
• W1957753312 hasConcept C95444343 @default.
• W1957753312 hasConceptScore W1957753312C140704245 @default.
• W1957753312 hasConceptScore W1957753312C153911025 @default.
• W1957753312 hasConceptScore W1957753312C158617107 @default.
• W1957753312 hasConceptScore W1957753312C159047783 @default.
• W1957753312 hasConceptScore W1957753312C190283241 @default.
• W1957753312 hasConceptScore W1957753312C2522874641 @default.
• W1957753312 hasConceptScore W1957753312C2776715637 @default.
• W1957753312 hasConceptScore W1957753312C2779635636 @default.
• W1957753312 hasConceptScore W1957753312C31573885 @default.
• W1957753312 hasConceptScore W1957753312C54355233 @default.
• W1957753312 hasConceptScore W1957753312C55493867 @default.
• W1957753312 hasConceptScore W1957753312C81885089 @default.
• W1957753312 hasConceptScore W1957753312C82210918 @default.
• W1957753312 hasConceptScore W1957753312C86803240 @default.
• W1957753312 hasConceptScore W1957753312C95444343 @default.
• W1957753312 hasIssue "6" @default.
• W1957753312 hasLocation W19577533121 @default.
• W1957753312 hasLocation W19577533122 @default.
• W1957753312 hasLocation W19577533123 @default.
• W1957753312 hasLocation W19577533124 @default.
• W1957753312 hasOpenAccess W1957753312 @default.

• next