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- W1958958870 abstract "Different human retroviruses, such as Human Immunodeficiency Virus (HIV) and Human T-cell Lymphotropic Virus (HTLV), can cause neurologic infection. However, a definitive diagnosis may be hampered by several factors. Quantification of the viral or proviral load in cerebrospinal fluid (CSF) may be helpful in the diagnosis of nervous system disorders due to retroviral infection and may influence the treatment approach. The present work discusses retrovirus infection and neurologic impairment, as well as the usefulness of the determination of the HIV and HTLV proviral or viral load in cerebrospinal fluid in cases of neurologic disorder, in light of recent advances in this field. This study also discusses the different molecular techniques for quantifying the proviral load (real-time quantitative PCR, droplet digital PCR, and semi-nested real-time reverse transcription PCR) that are currently available." @default.
- W1958958870 created "2016-06-24" @default.
- W1958958870 creator A5034242846 @default.
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- W1958958870 date "2015-08-08" @default.
- W1958958870 modified "2023-10-18" @default.
- W1958958870 title "Relevance of retrovirus quantification in cerebrospinal fluid for neurologic diagnosis" @default.
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- W1958958870 doi "https://doi.org/10.1186/s12929-015-0170-y" @default.
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